(Q54544192)

31 May 2018

title

The kinase Pyk2 is involved in renal fibrosis by means of mechanical stretch-induced growth factor expression in renal tubules. (English)

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31 May 2018

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Kazuhiro Sonomura

1

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31 May 2018

Mitsuhiko Okigaki

2

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31 May 2018

Taikou Kimura

3

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31 May 2018

Eiko Matsuoka

4

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31 May 2018

Yayoi Shiotsu

5

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31 May 2018

Takaomi Adachi

6

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31 May 2018

Hiroshi Kado

7

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31 May 2018

Ryo Ishida

8

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31 May 2018

Tetsuro Kusaba

9

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31 May 2018

Hiroaki Matsubara

10

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31 May 2018

Yasukiyo Mori

11

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31 May 2018

language of work or name

English

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publication date

7 December 2011

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31 May 2018

published in

Kidney International

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31 May 2018

volume

81

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31 May 2018

issue

5

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31 May 2018

page(s)

449-457

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31 May 2018

New insights into the consequences and mechanisms of renal impairment in obstructive nephropathy

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1 reference

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7 January 2021

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Obstructive nephropathy and renal fibrosis

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Increased oxidative stress in mouse kidneys with unilateral ureteral obstruction

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Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney

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Renal function after release of ureteral obstruction: role of endothelin and the renal artery endothelium

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Increased expression of TGF-beta 1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

RAFTK/Pyk2-mediated cellular signalling

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction

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7 January 2021

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

PYK2/CAKbeta represents a redox-sensitive tyrosine kinase in vascular smooth muscle cells

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

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7 January 2021

Actin-dependent regulation of connective tissue growth factor

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7 January 2021

Interaction of nitric oxide and transforming growth factor-beta1 induced by angiotensin II and mechanical stretch in rat renal tubular epithelial cells

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7 January 2021

RAFTK/PYK2-dependent and -independent apoptosis in multiple myeloma cells.

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7 January 2021

Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Activation of Pyk2 by stress signals and coupling with JNK signaling pathway

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Cyclic strain activates redox-sensitive proline-rich tyrosine kinase 2 (PYK2) in endothelial cells

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Regulation of the Tyrosine Kinase Pyk2 by Calcium Is through Production of Reactive Oxygen Species in Cytotoxic T Lymphocytes

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Stretch-activated channel activation promotes early afterdepolarizations in rat ventricular myocytes under oxidative stress

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7 January 2021

Mechanotransduction in the renal tubule

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7 January 2021

Mechanism of dietary salt-mediated increase in intravascular production of TGF-beta1.

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7 January 2021

Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis

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7 January 2021

Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Integrated actions of transforming growth factor-beta1 and connective tissue growth factor in renal fibrosis

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Connective tissue growth factor-(CTGF, CCN2)--a marker, mediator and therapeutic target for renal fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Quantification of renal pathology by image analysis

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https://api.crossref.org/works/10.1038%2FKI.2011.403

7 January 2021

Protamine augments stretch induced calcium increase in vascular endothelium

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7 January 2021

Direct aldosterone action as a profibrotic factor via ROS-mediated SGK1 in peritoneal fibroblasts

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7 January 2021

Identifiers

DOI

10.1038/KI.2011.403

1 reference

31 May 2018

1 reference

31 May 2018