(Q54561856)

1 June 2018

title

Combinatorial mutations of lac repressor. Stability of monomer-monomer interface is increased by apolar substitution at position 84. (English)

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1 June 2018

author name string

Nichols JC

series ordinal

1

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1 June 2018

Matthews KS

series ordinal

2

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1 June 2018

language of work or name

English

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publication date

1 July 1997

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1 June 2018

Journal of Biological Chemistry

published in

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1 June 2018

volume

272

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1 June 2018

issue

30

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1 June 2018

page(s)

18550-18557

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1 June 2018

Interaction of effecting ligands with lac repressor and repressor-operator complex

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Amino-Acid Sequence of lac Repressor from Escherichia coli. Isolation, Sequence Analysis and Sequence Assembly of Tryptic Peptides and Cyanogen-Bromide Fragments

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The Amino-Acid Sequence of lac Repressor

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Sequence of the lacI gene

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Molecular parameters characterizing the interaction of Escherichia coli lac repressor with non-operator DNA and inducer

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Lac repressor - lac operator interaction. Circular dichroism study

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Dissociation of the lactose repressor-operator DNA complex: effects of size and sequence context of operator-containing DNA.

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Crystal structure of lac repressor core tetramer and its implications for DNA looping

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Crystal structure of the lactose operon repressor and its complexes with DNA and inducer

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How lac Repressor Binds to DNA

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A comparison of lac repressor binding to operator and to nonoperator DNA

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Genetic studies of the lac repressor. XI. On aspects of lac repressor structure suggested by genetic experiments

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Genetic studies of the lac repressor. IX. Generation of altered proteins by the suppression of nonsence mutations

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An amino-terminal fragment of lac repressor binds specifically to lac operator

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Recognition helices of lac and lambda repressor are oriented in opposite directions and recognize similar DNA sequences

21 January 2018

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T41 mutation in lac repressor is Tyr282----Asp

21 January 2018

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Genetic studies of the lac repressor. XIII. Extensive amino acid replacements generated by the use of natural and synthetic nonsense suppressors

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Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as "spacers" which do not require a specific sequence.

21 January 2018

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Characterization of mutants affecting the KRK sequence in the carboxyl-terminal domain of lac repressor.

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Subunit dissociation affects DNA binding in a dimeric lac repressor produced by C-terminal deletion.

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Boundary analysis in sedimentation transport experiments: a procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile

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DNA binding of the lac repressor

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A double-filter method for nitrocellulose-filter binding: application to protein-nucleic acid interactions

21 January 2018

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The Stability of Globular Protein

21 January 2018

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Conformational change of the repressor induced with the inducer

21 January 2018

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Interaction of lac repressor with inducer. Kinetic and equilibrium measurements

21 January 2018

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DNA looping in cellular repression of transcription of the galactose operon

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21 January 2018

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Characterization and modification of a monomeric mutant of the lactose repressor protein

21 January 2018

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21 January 2018

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21 January 2018

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Allosteric regulation of inducer and operator binding to the lactose repressor

21 January 2018

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Cloning and characterization of several dominant-negative and tight-binding mutants of lac repressor

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.30.18550

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1 June 2018

PubMed ID

9228020

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1 June 2018