(Q54572507)

1 June 2018

title

Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia. (English)

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1 June 2018

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Junji Saruwatari

1

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Masayuki Matsunaga

2

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Kazuyuki Ikeda

3

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Masashi Nakao

4

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Kentaro Oniki

5

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Takayuki Seo

6

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Shuichi Mihara

7

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Toru Marubayashi

8

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Tetsuya Kamataki

9

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Kazuko Nakagawa

10

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publication date

7 November 2006

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1 June 2018

European Journal of Clinical Pharmacology

published in

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1 June 2018

volume

62

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issue

12

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1 June 2018

page(s)

995-1001

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1 June 2018

https://scigraph.springernature.com/pub.10.1007/s00228-006-0210-3

exact match

0 references

cites work

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Increased frequency of cytochrome P450 2D6 poor metabolizers among patients with metoprolol-associated adverse effects

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Evaluation of inhibitory drug interactions during drug development: genetic polymorphisms must be considered

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CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study.

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Pharmacokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension

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Pathway-selective sex differences in the metabolic clearance of propranolol in human subjects

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The impact of the CYP2D6 polymorphism on haloperidol pharmacokinetics and on the outcome of haloperidol treatment.

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Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes

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Extension of a pilot study: impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness.

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In vitro characterization of cytochrome P450 2D6 inhibition by classic histamine H1 receptor antagonists

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Formation of morphine from codeine in Chinese subjects of different CYP2D6 genotypes

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Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6

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Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes

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Propranolol disposition in Chinese subjects of different CYP2D6 genotypes

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Inhibitory effects of H1-antihistamines on CYP2D6- and CYP2C9-mediated drug metabolic reactions in human liver microsomes

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Effects of emedastine and cetirizine, alone and with alcohol, on actual driving of males and females

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12 December 2020

Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or low CYP2D6 activity

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12 December 2020

Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity

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12 December 2020

Increased risk of serious injury following an initial prescription for diphenhydramine

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12 December 2020

The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine

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12 December 2020

Sensitivity and specificity of the multiple sleep latency test (MSLT), the maintenance of wakefulness test and the epworth sleepiness scale: failure of the MSLT as a gold standard

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Tardive dyskinesia and debrisoquine 4-hydroxylase (CYP2D6) genotype in Japanese schizophrenics.

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The influence of sex on pharmacokinetics

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12 December 2020

Impact of CYP2D6 genotype on adverse effects during treatment with metoprolol: a prospective clinical study

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12 December 2020

Effects of the CYP2D6 genotype on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese schizophrenic patients

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Antipsychotic-induced extrapyramidal syndromes and cytochrome P450 2D6 genotype: a case-control study

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12 December 2020

Bioequivalence revisited: influence of age and sex on CYP enzymes

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12 December 2020

Effects of desloratadine, diphenhydramine, and placebo on driving performance and psychomotor performance measurements

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12 December 2020

10.1007/S00228-006-0210-3

Identifiers

DOI

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1 June 2018

PubMed ID

17089107

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1 June 2018