(Q54583730)

1 June 2018

title

Intra- and inter-ethnic differences in the allele frequencies of cytochrome P450 2B6 gene in Chinese. (English)

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1 June 2018

author name string

Su Guan

1

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1 June 2018

Min Huang

2

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1 June 2018

Xin Li

3

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1 June 2018

Xiao Chen

4

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1 June 2018

Eli Chan

5

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1 June 2018

Shu-Feng Zhou

6

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1 June 2018

publication date

9 August 2006

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1 June 2018

published in

Pharmaceutical Research

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1 June 2018

volume

23

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1 June 2018

issue

9

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1 June 2018

page(s)

1983-1990

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1 June 2018

Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissues

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Gender difference in ifosfamide metabolism by human liver microsomes

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Inhibition of human CYP2B6 by N,N',N''-triethylenethiophosphoramide is irreversible and mechanism-based

21 January 2018

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Inhibitory monoclonal antibody to human cytochrome P450 2B6.

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Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes

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Allele and genotype frequencies of CYP2B6 and CYP3A5 in the Japanese population

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Further characterization of the expression in liver and catalytic activity of CYP2B6.

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Two-sided confidence intervals for the single proportion: comparison of seven methods

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Nonlinear pharmacokinetics of cyclophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation

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The major phenobarbital-inducible cytochrome P-450 gene subfamily (P450IIB) mapped to the long arm of human chromosome 19

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Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study

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12 December 2020

An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters: experience in Singapore

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12 December 2020

Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: demonstration of phenotypic null alleles

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12 December 2020

cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver

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12 December 2020

Interethnic variability in human drug responses.

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Potent Mechanism-Based Inhibition of Human CYP2B6 by Clopidogrel and Ticlopidine

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Cytochrome P450 isozymes responsible for the metabolism of toluene and styrene in human liver microsomes

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The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

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12 December 2020

Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese.

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Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

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12 December 2020

Individual variation in the activation and inactivation of metabolic pathways of cyclophosphamide

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12 December 2020

Structure-function analysis of human cytochrome P-450 2B6 using a novel substrate, site-directed mutagenesis, and molecular modeling.

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12 December 2020

Summary of information on human CYP enzymes: human P450 metabolism data

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12 December 2020

Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism

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12 December 2020

Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz

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12 December 2020

A single nucleotide polymorphism of CYP2b6 found in Japanese enhances catalytic activity by autoactivation

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12 December 2020

Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism

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12 December 2020

Molecular basis of ethnic differences in drug disposition and response

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12 December 2020

Human CYP2B6: expression, inducibility and catalytic activities

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Influence of 516G>T polymorphisms at the gene encoding the CYP450-2B6 isoenzyme on efavirenz plasma concentrations in HIV-infected subjects

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Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin

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Functional characterization of cytochrome P450 2B6 allelic variants

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Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients

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Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors

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Metabolism of levo-alpha-Acetylmethadol (LAAM) by human liver cytochrome P450: involvement of CYP3A4 characterized by atypical kinetics with two binding sites

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Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes

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Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites

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Cyclophosphamide pharmacokinetics in children

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Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.

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Disposition and biotransformation of the antiretroviral drug nevirapine in humans.

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12 December 2020

Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity.

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12 December 2020

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

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12 December 2020

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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12 December 2020

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz

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12 December 2020

Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes

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12 December 2020

Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine

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12 December 2020

Haplotype structure and allele frequencies of CYP2B6 in a Korean population.

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12 December 2020

Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling

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12 December 2020

A natural CYP2B6 TATA box polymorphism (-82T--> C) leading to enhanced transcription and relocation of the transcriptional start site.

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12 December 2020

Examination of purported probes of human CYP2B6.

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12 December 2020

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

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12 December 2020

10.1007/S11095-006-9083-5

Identifiers

DOI

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1 June 2018

PubMed ID

16951995

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1 June 2018