(Q54584689)

1 June 2018

title

Effect of CYP2D6 genotype on flecainide pharmacokinetics in Japanese patients with supraventricular tachyarrhythmia. (English)

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1 June 2018

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Kosuke Doki

1

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1 June 2018

Masato Homma

2

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1 June 2018

Keisuke Kuga

3

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1 June 2018

Kazutomi Kusano

4

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1 June 2018

Shigeyuki Watanabe

5

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1 June 2018

Iwao Yamaguchi

6

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1 June 2018

Yukinao Kohda

7

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1 June 2018

publication date

30 August 2006

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1 June 2018

European Journal of Clinical Pharmacology

published in

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1 June 2018

volume

62

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1 June 2018

issue

11

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1 June 2018

page(s)

919-926

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1 June 2018

https://scigraph.springernature.com/pub.10.1007/s00228-006-0188-x

exact match

0 references

cites work

Flecainide pharmacokinetics after multiple dosing in patients with impaired renal function

1 reference

https://api.crossref.org/works/10.1007%2FS00228-006-0188-X

Flecainide pharmacokinetics in healthy volunteers: the influence of urinary pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-006-0188-X

New antiarrhythmic drugs: tocainide, mexiletine, flecainide, encainide, and amiodarone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-006-0188-X

The influence of urinary pH on flecainide excretion and its serum pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-006-0188-X

Life-threatening flecainide toxicity. A pharmacodynamic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-006-0188-X

Bioinformatics research on inter-racial difference in drug metabolism I. Analysis on frequencies of mutant alleles and poor metabolizers on CYP2D6 and CYP2C19

21 January 2018

1 reference

12 December 2020

Assessment of serum flecainide trough levels in patients with tachyarrhythmia

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12 December 2020

Flecainide acetate for conversion of acute supraventricular tachycardia to sinus rhythm

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12 December 2020

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12 December 2020

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12 December 2020

High-throughput detection of multiple genetic polymorphisms influencing drug metabolism with mismatch primers in allele-specific polymerase chain reaction.

1 reference

12 December 2020

Pharmacokinetics of flecainide in patients with cirrhosis of the liver

1 reference

12 December 2020

Relationship between plasma concentrations and suppression of ventricular extrasystoles by flecainide acetate (R-818), a new antiarrhythmic, in patients

1 reference

12 December 2020

Absorption kinetics and pharmacodynamics of two oral dosage forms of flecainide in patients with an episode of paroxysmal atrial fibrillation

1 reference

12 December 2020

Simultaneous determination of serum flecainide and its metabolites by using high performance liquid chromatography

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12 December 2020

Elimination of flecainide as a function of urinary flow rate and pH

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12 December 2020

Outpatient treatment of recent-onset atrial fibrillation with the "pill-in-the-pocket" approach

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12 December 2020

Pharmacodynamics and side effects of flecainide acetate

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12 December 2020

Appropriate dosing of antiarrhythmic drugs in Japan requires therapeutic drug monitoring

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12 December 2020

Impact of CYP2C9 and CYP2C19 polymorphisms on tolbutamide kinetics and the insulin and glucose response in healthy volunteers

1 reference

12 December 2020

Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese

1 reference

12 December 2020

Metabolism of flecainide

1 reference

12 December 2020

Variable disposition kinetics and electrocardiographic effects of flecainide during repeated dosing in humans: contribution of genetic factors, dose-dependent clearance, and interaction with amiodarone

1 reference

12 December 2020

The influence of the sparteine/debrisoquin phenotype on the disposition of flecainide

1 reference

12 December 2020

Absorption kinetics of oral and rectal flecainide in healthy subjects

1 reference

12 December 2020

The decreased in vivo clearance of CYP2D6 substrates by CYP2D6*10 might be caused not only by the low-expression but also by low affinity of CYP2D6.

1 reference

12 December 2020

Analysis of the CYP2D6 gene in relation to dextromethorphan O-demethylation capacity in a Japanese population

1 reference

12 December 2020

Bioequivalence revisited: influence of age and sex on CYP enzymes

1 reference

12 December 2020

10.1007/S00228-006-0188-X

Identifiers

DOI

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1 June 2018

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1 June 2018