(Q54597890)

1 June 2018

title

Regulation of Akt and Wnt signaling by the group II metabotropic glutamate receptor antagonist LY341495 and agonist LY379268. (English)

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1 June 2018

author name string

Laurie P Sutton

series ordinal

1

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1 June 2018

Walter J Rushlow

series ordinal

2

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1 June 2018

language of work or name

English

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publication date

13 May 2011

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1 June 2018

Journal of Neurochemistry

published in

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1 June 2018

volume

117

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1 June 2018

issue

6

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1 June 2018

page(s)

973-983

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1 June 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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Antipsychotics alter the protein expression levels of beta-catenin and GSK-3 in the rat medial prefrontal cortex and striatum

21 January 2018

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The effects of antipsychotics on beta-catenin, glycogen synthase kinase-3 and dishevelled in the ventral midbrain of rats

21 January 2018

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Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

21 January 2018

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Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo

21 January 2018

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Habituation deficits induced by metabotropic glutamate receptors 2/3 receptor blockade in mice: reversal by antipsychotic drugs.

21 January 2018

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Regulation of neurotransmitter release by metabotropic glutamate receptors

21 January 2018

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Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Abnormalities of Wnt signalling in schizophrenia--evidence for neurodevelopmental abnormality.

21 January 2018

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Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

21 January 2018

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In vitro and in vivo evidence for a lack of interaction with dopamine D2 receptors by the metabotropic glutamate 2/3 receptor agonists 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-bicaroxylate monohydrate (LY354740) and (-)-2-oxa-4-aminobicyclo[3.1.0

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action

21 January 2018

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Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity

21 January 2018

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Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia.

21 January 2018

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Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors.

21 January 2018

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Dishevelled-2 maps to human chromosome 17 and distal to Wnt3a and vestigial tail (vt) on mouse chromosome 11

21 January 2018

1 reference

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Selective action of (-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268), a group II metabotropic glutamate receptor agonist, on basal and phencyclidine-induced dopamine release in the nucleus accumbens shell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

The human frizzled-3 (FZD3) gene on chromosome 8p21, a receptor gene for Wnt ligands, is associated with the susceptibility to schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Use of MGLUR2 and MGLUR3 knockout mice to explore in vivo receptor specificity of the MGLUR2/3 selective antagonist LY341495.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Molecular characterization and localization of human metabotropic glutamate receptor type 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Dishevelled: a mobile scaffold catalyzing development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Increased expression of Wnt-1 in schizophrenic brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Further evidence for a functional role of the glutamate receptor gene GRM3 in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Metabotropic glutamate receptors: physiology, pharmacology, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Signaling through beta-catenin and Lef/Tcf

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 increase locomotor activity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Dynamic recruitment of axin by Dishevelled protein assemblies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Phencyclidine and glutamate agonist LY379268 stimulate dopamine D2High receptors: D2 basis for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Glutamate agonists for treating schizophrenia have affinity for dopamine D2High and D3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Dopamine partial agonist actions of the glutamate receptor agonists LY 354,740 and LY 379,268.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Human dishevelled genes constitute a DHR-containing multigene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Association study of GSK3 gene polymorphisms with schizophrenia and clozapine response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Activation of the canonical Wnt pathway by the antipsychotics haloperidol and clozapine involves dishevelled-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

cDNA cloning and properties of glycogen synthase kinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

The dishevelled protein is modified by wingless signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Abundance, complexation, and trafficking of Wnt/beta-catenin signaling elements in response to Wnt3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

Positive association of the human frizzled 3 (FZD3) gene haplotype with schizophrenia in Chinese Han population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07268.X

10.1111/J.1471-4159.2011.07268.X

21 January 2018

Identifiers

DOI

1 reference

1 June 2018

PubMed ID

21477044

1 reference

1 June 2018