(Q54600278)

1 June 2018

title

Human C-reactive protein exacerbates metabolic disorders in association with adipose tissue remodelling. (English)

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1 June 2018

author name string

Hidehiro Kaneko

1

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1 June 2018

Toshihisa Anzai

2

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1 June 2018

Toshiyuki Nagai

3

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1 June 2018

Atsushi Anzai

4

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1 June 2018

Toshiyuki Takahashi

5

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1 June 2018

Yoshinori Mano

6

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1 June 2018

Kohkichi Morimoto

7

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1 June 2018

Yuichiro Maekawa

8

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1 June 2018

Hiroshi Itoh

9

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1 June 2018

Tsutomu Yoshikawa

10

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Satoshi Ogawa

11

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1 June 2018

Keiichi Fukuda

12

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1 June 2018

publication date

29 March 2011

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1 June 2018

published in

Cardiovascular Research

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1 June 2018

volume

91

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1 June 2018

issue

3

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1 June 2018

page(s)

546-555

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1 June 2018

C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women

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C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

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C-reactive protein inhibits insulin activation of endothelial nitric oxide synthase via the immunoreceptor tyrosine-based inhibition motif of FcgammaRIIB and SHIP-1.

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The major receptor for C-reactive protein on leukocytes is fcgamma receptor II.

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C-reactive protein overexpression exacerbates pressure overload-induced cardiac remodeling through enhanced inflammatory response.

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C-reactive protein promotes monocyte chemoattractant protein-1--mediated chemotaxis through upregulating CC chemokine receptor 2 expression in human monocytes

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C-reactive protein induces M-CSF release and macrophage proliferation

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Obesity is associated with macrophage accumulation in adipose tissue

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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CCR2 modulates inflammatory and metabolic effects of high-fat feeding

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A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha

21 January 2018

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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

21 January 2018

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Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance

21 January 2018

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

21 January 2018

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PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

21 January 2018

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C-reactive protein inhibits adiponectin gene expression and secretion in 3T3-L1 adipocytes

21 January 2018

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A central role for JNK in obesity and insulin resistance

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Nonalcoholic fatty liver disease: a feature of the metabolic syndrome

21 January 2018

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High-sensitivity C-reactive protein is an independent clinical feature of nonalcoholic steatohepatitis (NASH) and also of the severity of fibrosis in NASH.

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Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice

21 January 2018

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Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (Fc gamma RI)-dependent.

21 January 2018

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C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/CVR/CVR088

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1 June 2018

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1 June 2018