(Q54611511)

1 June 2018

title

Klotho suppresses RIG-I-mediated senescence-associated inflammation. (English)

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1 June 2018

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Feng Liu

1

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1 June 2018

Su Wu

series ordinal

2

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1 June 2018

Hongwei Ren

series ordinal

3

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1 June 2018

Jun Gu

series ordinal

4

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1 June 2018

publication date

20 February 2011

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1 June 2018

published in

Nature Cell Biology

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1 June 2018

volume

13

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1 June 2018

issue

3

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1 June 2018

page(s)

254-262

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1 June 2018

https://scigraph.springernature.com/pub.10.1038/ncb2167

exact match

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cites work

Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system

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12 December 2020

VISA is an adapter protein required for virus-triggered IFN-beta signaling

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12 December 2020

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

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12 December 2020

Klotho is a serum factor related to human aging

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12 December 2020

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

12 December 2020

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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12 December 2020

Retinoic acid-inducible gene-I is induced in gingival fibroblasts by lipopolysaccharide or poly IC: possible roles in interleukin-1beta, -6 and -8 expression.

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12 December 2020

Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress.

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12 December 2020

Retinoic acid-inducible gene-I mediates late phase induction of TNF-alpha by lipopolysaccharide

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12 December 2020

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

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12 December 2020

Role of p14(ARF) in replicative and induced senescence of human fibroblasts

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12 December 2020

Augmented Wnt signaling in a mammalian model of accelerated aging

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12 December 2020

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

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12 December 2020

Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases

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12 December 2020

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

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12 December 2020

Tumor-necrosis factor-alpha induces retinoic acid-inducible gene-I in rheumatoid fibroblast-like synoviocytes

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12 December 2020

Retinoic acid-inducible gene-I is constitutively expressed and involved in IFN-gamma-stimulated CXCL9-11 production in intestinal epithelial cells

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12 December 2020

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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12 December 2020

Oxidative stress decreases klotho expression in a mouse kidney cell line.

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12 December 2020

Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

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12 December 2020

Chemokine signaling via the CXCR2 receptor reinforces senescence

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12 December 2020

Klotho protein protects against endothelial dysfunction

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12 December 2020

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

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The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel

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Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein

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12 December 2020

Regulation of fibroblast growth factor-23 signaling by klotho

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12 December 2020

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

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12 December 2020

The serial cultivation of human diploid cell strains

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12 December 2020

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

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12 December 2020

Klotho suppresses TNF-alpha-induced expression of adhesion molecules in the endothelium and attenuates NF-kappaB activation

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12 December 2020

Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein

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12 December 2020

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

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12 December 2020

Regulation of oxidative stress by the anti-aging hormone klotho

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12 December 2020

C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence.

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12 December 2020

Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway

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12 December 2020

Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells

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12 December 2020

Retinoic acid-inducible gene-I (RIG-I) is induced by IFN-{gamma} in human mesangial cells in culture: possible involvement of RIG-I in the inflammation in lupus nephritis

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12 December 2020

Suppression of aging in mice by the hormone Klotho

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12 December 2020

Involvement of retinoic acid-inducible gene-I in inflammation of rheumatoid fibroblast-like synoviocytes.

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12 December 2020

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

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12 December 2020

Klotho converts canonical FGF receptor into a specific receptor for FGF23

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12 December 2020

Microarray analysis of replicative senescence

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12 December 2020

Cell type-specific involvement of RIG-I in antiviral response

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12 December 2020

Identifiers

DOI

10.1038/NCB2167

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1 June 2018

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1 June 2018