(Q54626064)

1 June 2018

title

Rakicidin A effectively induces apoptosis in hypoxia adapted Bcr-Abl positive leukemic cells. (English)

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1 June 2018

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Miki Takeuchi

1

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1 June 2018

Eishi Ashihara

2

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1 June 2018

Yohko Yamazaki

3

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1 June 2018

Shinya Kimura

4

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1 June 2018

Yoko Nakagawa

5

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1 June 2018

Ruriko Tanaka

6

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1 June 2018

Hisayuki Yao

7

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1 June 2018

Rina Nagao

8

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Yoshihiro Hayashi

9

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Hideyo Hirai

10

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1 June 2018

Taira Maekawa

11

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1 June 2018

publication date

19 December 2010

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1 June 2018

published in

Cancer Science

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1 June 2018

volume

102

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issue

3

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1 June 2018

page(s)

591-596

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1 June 2018

Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy

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Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

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Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in a hypoxic environment

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Rakicidin A: a hypoxia-selective cytotoxin

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Antiproliferative efficacy of the third-generation bisphosphonate, zoledronic acid, combined with other anticancer drugs in leukemic cell lines

21 January 2018

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The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias

21 January 2018

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A novel mechanism for imatinib mesylate-induced cell death of BCR-ABL-positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity

21 January 2018

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A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro

21 January 2018

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Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

21 January 2018

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Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

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Increased cellular hypoxia and reduced proliferation of both normal and leukaemic cells during progression of acute myeloid leukaemia in rats.

21 January 2018

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Severe hypoxia defines heterogeneity and selects highly immature progenitors within clonal erythroleukemia cells.

21 January 2018

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Imatinib therapy in chronic myelogenous leukemia: strategies to avoid and overcome resistance

21 January 2018

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Hypoxia modifies proliferation and differentiation of CD34(+) CML cells

21 January 2018

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Suppression of postmitochondrial signaling and delayed response to UV-induced nuclear apoptosis in HeLa cells

21 January 2018

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Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria

21 January 2018

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Micro-calpain regulates caspase-dependent and apoptosis inducing factor-mediated caspase-independent apoptotic pathways in cisplatin-induced apoptosis

21 January 2018

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21 January 2018

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Comparison of in vivo efficacy of hypoxic cytotoxin tirapazamine and hypoxic cell radiosensitizer KU-2285 in combination with single and fractionated irradiation.

21 January 2018

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Usefulness of tirapazamine as a combined agent in chemoradiation and thermo-chemoradiation therapy at mild temperatures: reference to the effect on intratumor quiescent cells.

21 January 2018

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Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinones

21 January 2018

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Free radicals and anticancer drug resistance: oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01813.X

10.1111/J.1349-7006.2010.01813.X

21 January 2018

Identifiers

DOI

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1 June 2018

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1 June 2018