(Q54640476)

1 June 2018

title

Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure. (English)

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1 June 2018

1 reference

Radko Komers

1

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1 June 2018

Terry T Oyama

2

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1 June 2018

Douglas R Beard

3

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1 June 2018

Chris Tikellis

4

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1 June 2018

Bei Xu

5

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1 June 2018

Daniel F Lotspeich

6

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1 June 2018

Sharon Anderson

7

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1 June 2018

language of work or name

English

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publication date

20 October 2010

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1 June 2018

published in

Kidney International

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1 June 2018

volume

79

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1 June 2018

issue

4

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1 June 2018

page(s)

432-442

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1 June 2018

https://scigraph.springernature.com/pub.10.1038/ki.2010.428

exact match

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cites work

RhoA and resistance artery remodeling.

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https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Role of Rho-kinase and p27 in angiotensin II-induced vascular injury

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https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats

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https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Involvements of Rho-kinase and TGF-beta pathways in aldosterone-induced renal injury

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https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Effect of fasudil on Rho-kinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

RhoA/Rho-kinase contribute to the pathogenesis of diabetic renal disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Long-term administration of rho-kinase inhibitor ameliorates renal damage in malignant hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Fasudil, a Rho-kinase inhibitor, attenuates glomerulosclerosis in Dahl salt-sensitive rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Crucial role of Rho-nuclear factor-kappaB axis in angiotensin II-induced renal injury

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Anti-anginal effect of fasudil, a Rho-kinase inhibitor, in patients with stable effort angina: a multicenter study

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

High glucose-induced upregulation of osteopontin is mediated via Rho/Rho kinase pathway in cultured rat aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Upregulation of small GTPase RhoA in the basilar artery from diabetic (mellitus) rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Nifedipine versus fosinopril in uninephrectomized diabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Irbesartan normalises the deficiency in glomerular nephrin expression in a model of diabetes and hypertension

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Inhibition of Rho-kinase attenuates nephrosclerosis and improves survival in salt-loaded spontaneously hypertensive stroke-prone rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

A Rho-kinase inhibitor, fasudil, prevents development of diabetes and nephropathy in insulin-resistant diabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Regression of glomerular injury by losartan in experimental diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Vessel- and vasoconstrictor-dependent role of rho/rho-kinase in renal microvascular tone

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Effects of angiotensin II, arginine vasopressin and tromboxane A2 in renal vascular bed: role of rho-kinase

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Negative regulation of RhoA/Rho kinase by angiotensin II type 2 receptor in vascular smooth muscle cells: role in angiotensin II-induced vasodilation in stroke-prone spontaneously hypertensive rats.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Upregulation of osteopontin gene expression in diabetic rat proximal tubular cells revealed by microarray profiling

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

TGF-beta and epithelial-to-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3β, Snail1, and β-catenin in renal proximal tubule cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

RhoGTPase activation is a key step in renal epithelial mesenchymal transdifferentiation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Pharmacological modulation of epithelial mesenchymal transition caused by angiotensin II. Role of ROCK and MAPK pathways.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Angiotensin AT1 receptor activation mediates high glucose-induced epithelial-mesenchymal transition in renal proximal tubular cells.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Slug is required for cell survival during partial epithelial-mesenchymal transition of HGF-induced tubulogenesis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Increased E-cadherin expression in the ligated kidney following unilateral ureteric obstruction

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Changes in the expression of nephrin gene and protein in experimental diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Endothelial dysfunction as a modifier of angiogenic response in Zucker diabetic fat rat: amelioration with Ebselen

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Increased glomerular capillary pressure alters glomerular cytokine expression

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

mRNA translation: unexplored territory in renal science

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

High glucose, high insulin, and their combination rapidly induce laminin-beta1 synthesis by regulation of mRNA translation in renal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration by rapamycin

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Effects of the combination of an angiotensin II antagonist with an HMG-CoA reductase inhibitor in experimental diabetes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Altered endothelial nitric oxide synthase targeting and conformation and caveolin-1 expression in the diabetic kidney.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Renal p38 MAP kinase activity in experimental diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.428

7 January 2021

Identifiers

DOI

10.1038/KI.2010.428

1 reference

1 June 2018

release_trcaf5myirechdm4m2x3p6f7sq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/trcaf5myirechdm4m2x3p6f7sq

24 November 2022

mapped directly with Wikidata item

PubMed ID

20962741

1 reference

1 June 2018