(Q54658982)

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Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics.

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1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics. (English)

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

Streptococcus pneumoniae

1 reference

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author name string

Mouz N

1

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

Di Guilmi AM

2

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

Gordon E

3

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

Hakenbeck R

4

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

Dideberg O

5

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

Vernet T

6

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

language of work or name

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publication date

1 July 1999

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

Journal of Biological Chemistry

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Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

274

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Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

19175-19180

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

27

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

Penicillin: its basic site of action as an inhibitor of a peptide cross-linking reaction in cell wall mucopeptide synthesis

1 reference

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21 January 2018

Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine

1 reference

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21 January 2018

Extensive re-modelling of the transpeptidase domain of penicillin-binding protein 2B of a penicillin-resistant South African isolate of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Interspecies recombinational events during the evolution of altered PBP 2x genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Penicillin-resistant viridans streptococci have obtained altered penicillin-binding protein genes from penicillin-resistant strains of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Relatedness among penicillin-binding protein 2b genes of Streptococcus mitis, Streptococcus oralis, and Streptococcus pneumoniae.

1 reference

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21 January 2018

Mosaic pbpX genes of major clones of penicillin-resistant Streptococcus pneumoniae have evolved from pbpX genes of a penicillin-sensitive Streptococcus oralis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Identification of a structural determinant for resistance to beta-lactam antibiotics in Gram-positive bacteria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Genetic analysis of clinical isolates of Streptococcus pneumoniae with high-level resistance to expanded-spectrum cephalosporins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

A global gene pool for high-level cephalosporin resistance in commensal Streptococcus species and Streptococcus pneumoniae

1 reference

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21 January 2018

Penicillin-binding protein 2x of Streptococcus pneumoniae. Expression in Escherichia coli and purification of a soluble enzymatically active derivative

1 reference

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21 January 2018

Biochemical characterization of penicillin-resistant and -sensitive penicillin-binding protein 2x transpeptidase activities of Streptococcus pneumoniae and mechanistic implications in bacterial resistance to beta-lactam antibiotics

1 reference

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21 January 2018

The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Five independent combinations of mutations can result in low-affinity penicillin-binding protein 2x of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Electrostatic steering and ionic tethering in enzyme-ligand binding: insights from simulations

1 reference

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21 January 2018

Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases

1 reference

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21 January 2018

More extended-spectrum beta-lactamases

1 reference

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21 January 2018

Characterization of the plasmid genes blaT-4 and blaT-5 which encode the broad-spectrum beta-lactamases TEM-4 and TEM-5 in enterobacteriaceae.

1 reference

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21 January 2018

Raster3D Version 2.0. A program for photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Localized sex in bacteria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Genetics of resistance to third-generation cephalosporins in clinical isolates of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Penicillin binding protein 2x as a major contributor to intrinsic beta-lactam resistance of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.19175

21 January 2018

Identifiers

10.1074/JBC.274.27.19175

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/10383423

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