(Q54667913)

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Guanine-nucleotide binding activity, interaction with GTPase-activating protein and solution conformation of the human c-Ha-Ras protein catalytic domain are retained upon deletion of C-terminal 18 amino acid residues.

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

Guanine-nucleotide binding activity, interaction with GTPase-activating protein and solution conformation of the human c-Ha-Ras protein catalytic domain are retained upon deletion of C-terminal 18 amino acid residues. (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

Junko Fujita-Yoshigaki

1

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

2

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

author name string

K Yamasaki

3

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

Y Muto

4

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

T Miyazawa

5

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

S Nishimura

6

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

S Yokoyama

7

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

publication date

1 December 1992

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

The Protein Journal

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Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

11

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Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

6

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

731-739

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

https://scigraph.springernature.com/pub.10.1007/bf01024974

0 references

Spin-labeling proton NMR study on aromatic amino acid residues in the guanine nucleotide binding site of human c-Ha-ras(1-171) protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p21 ras C-terminus is required for transformation and membrane association

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformation of guanosine 5'-diphosphate as bound to a human c-Ha-ras mutant protein: a nuclear Overhauser effect study

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human-tumor-derived cell lines contain common and different transforming genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming activity of human tumor DNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proton NMR studies of the GDP.Mg2+ complex of the Ha-ras oncogene product p21

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proton NMR studies of transforming and nontransforming H-ras p21 mutants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and dynamic differences between normal and transforming N-ras gene products: a 31P and isotope-edited 1H NMR study

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformation change of effector-region residues in antiparallel β-sheet of human c-Ha-ras protein on GDP→GTPγS exchange: A two-dimensional NMR study

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of bovine GAP and its interaction with oncogenic ras p21.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of the carboxyl terminus of the p21 protein. Structural relationship to the nucleotide-binding/transforming regions of the protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of resonances from an oncogenic activating locus of human N-RAS-encoded p21 protein using isotope-edited NMR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AN UNIDENTIFIED VIRUS WHICH CAUSES THE RAPID PRODUCTION OF TUMOURS IN MICE.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and expression of a synthetic gene for the activated human c-Ha-ras protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microinjection of the oncogene form of the human H-ras (T-24) protein results in rapid proliferation of quiescent cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast and mammalian ras proteins have conserved biochemical properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xenopus oocyte germinal-vesicle breakdown induced by [Val12]Ras is inhibited by a cytosol-localized Ras mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMR study of the phosphoryl binding loop in purine nucleotide proteins: evidence for strong hydrogen bonding in human N-ras p21.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of ras proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A1H-15N NM R study of human c-Ha-ras protein: Biosynthetic incorporation of15N-labeled amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/1466766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF01024974

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/1466766

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