(Q54703703)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15340260%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer (English)

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1 January 2020

1 reference

1 reference

5

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1 January 2020

author name string

A McGivern

1

1 reference

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1 January 2020

C V A Wynter

2

1 reference

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1 January 2020

V L J Whitehall

3

1 reference

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1 January 2020

T Kambara

4

1 reference

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1 January 2020

M D Walsh

6

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1 January 2020

M A Barker

7

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1 January 2020

S Arnold

8

1 reference

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1 January 2020

L A Simms

9

1 reference

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1 January 2020

B A Leggett

10

1 reference

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1 January 2020

J Young

11

1 reference

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1 January 2020

J R Jass

12

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1 January 2020

publication date

1 January 2004

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1 January 2020

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1 January 2020

volume

3

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1 January 2020

page(s)

101-107

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1 January 2020

issue

2

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https://scigraph.springernature.com/pub.10.1023/b:fame.0000039861.30651.c8

1 January 2020

exact match

0 references

cites work

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Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers

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Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation

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Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability.

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Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status

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Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis

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12 December 2020

Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis

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12 December 2020

Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability.

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Association between CpG island methylation and microsatellite instability in colorectal cancer

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12 December 2020

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

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12 December 2020

Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas.

1 reference

12 December 2020

The role of hypermethylation of the hMLH1 promoter region in HNPCC versus MSI+ sporadic colorectal cancers

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12 December 2020

DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer.

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12 December 2020

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12 December 2020

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways

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12 December 2020

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12 December 2020

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

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Important microsatellite markers in the investigation of replication errors (RER) in colorectal carcinomas

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12 December 2020

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12 December 2020

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12 December 2020

Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification

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12 December 2020

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12 December 2020

HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers

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12 December 2020

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12 December 2020

BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair

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12 December 2020

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12 December 2020

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

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12 December 2020

Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer

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12 December 2020

Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability

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12 December 2020

Methylation pattern of different regions of theMLH1 promoter and silencing of gene expression in hereditary and sporadic colorectal cancer

1 reference

12 December 2020

A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting Highlights and Bethesda Guidelines

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12 December 2020

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.

1 reference

12 December 2020

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

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12 December 2020

Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability

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12 December 2020

Aging and DNA methylation in colorectal mucosa and cancer

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12 December 2020