(Q54749851)

3 June 2018

title

V(D)J recombination and RAG-mediated transposition in yeast. (English)

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3 June 2018

author

James E. Haber

3

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3 June 2018

author name string

Anne E Clatworthy

1

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3 June 2018

Maria A Valencia

2

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3 June 2018

Marjorie A Oettinger

4

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3 June 2018

publication date

1 August 2003

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3 June 2018

published in

Molecular Cell

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3 June 2018

volume

12

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3 June 2018

issue

2

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3 June 2018

page(s)

489-499

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3 June 2018

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

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The mechanism and regulation of chromosomal V(D)J recombination

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Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

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ClpX-mediated remodeling of mu transpososomes: selective unfolding of subunits destabilizes the entire complex

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Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein

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Nonhomologous end joining and V(D)J recombination require an additional factor

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The C-terminal portion of RAG2 protects against transposition in vitro

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HDF2, the second subunit of the Ku homologue from Saccharomyces cerevisiae.

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

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A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

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V(D)J recombination: RAG proteins, repair factors, and regulation

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Requirement for the SRS2 DNA helicase gene in non-homologous end joining in yeast

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DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations.

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Mutational analysis of all conserved basic amino acids in RAG-1 reveals catalytic, step arrest, and joining-deficient mutants in the V(D)J recombinase

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The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

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7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

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In vivo transposition mediated by V(D)J recombinase in human T lymphocytes

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Cytotype control of Drosophila P element transposition: the 66 kd protein is a repressor of transposase activity.

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Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

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7 January 2021

Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination

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Tn5 as a model for understanding DNA transposition

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7 January 2021

V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

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7 January 2021

Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs.

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7 January 2021

Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair

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7 January 2021

Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2

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7 January 2021

Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination

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7 January 2021

Stimulation of V(D)J cleavage by high mobility group proteins

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7 January 2021

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7 January 2021

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

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7 January 2021

Joining-deficient RAG1 mutants block V(D)J recombination in vivo and hairpin opening in vitro

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7 January 2021

Simple and efficient generation in vitro of nested deletions and inversions: Tn5 intramolecular transposition

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7 January 2021

10.1016/S1097-2765(03)00305-8

Identifiers

DOI

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3 June 2018

PubMed ID

14536087

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3 June 2018