(Q55042094)

16 June 2018

title

Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia. (English)

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16 June 2018

author name string

Isabelle Rieu

1

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16 June 2018

Michèle Balage

2

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16 June 2018

Claire Sornet

3

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16 June 2018

Christophe Giraudet

4

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16 June 2018

Estelle Pujos

5

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16 June 2018

Jean Grizard

6

1 reference

16 June 2018

Laurent Mosoni

7

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16 June 2018

Dominique Dardevet

8

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16 June 2018

language of work or name

English

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publication date

15 June 2006

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16 June 2018

published in

Journal of Physiology

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16 June 2018

volume

575

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16 June 2018

issue

Pt 1

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16 June 2018

page(s)

305-315

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16 June 2018

Leucine: a key amino acid in ageing-associated sarcopenia?

cites work

1 reference

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A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Assessment of branched-chain amino Acid status and potential for biomarkers

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Oral leucine administration stimulates protein synthesis in rat skeletal muscle

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Physiological rise in plasma leucine stimulates muscle protein synthesis in neonatal pigs by enhancing translation initiation factor activation

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Differential effects of insulin and dietary amino acids on muscle protein synthesis in adult and old rats

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Mitochondrial and sarcoplasmic proteins, but not myosin heavy chain, are sensitive to leucine supplementation in old rat skeletal muscle

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Amino acid ingestion improves muscle protein synthesis in the young and elderly

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Oral and intravenously administered amino acids produce similar effects on muscle protein synthesis in the elderly.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Basal muscle amino acid kinetics and protein synthesis in healthy young and older men

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Latency and duration of stimulation of human muscle protein synthesis during continuous infusion of amino acids

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Protein pulse feeding improves protein retention in elderly women.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Exogenous amino acids stimulate net muscle protein synthesis in the elderly

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Effects of amino acids on synthesis and degradation of skeletal muscle proteins in humans.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Renal functional reserve in healthy elderly subjects.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Insulin and insulin-like growth factor-I enhance human skeletal muscle protein anabolism during hyperaminoacidemia by different mechanisms

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Branched-chain amino acid metabolism

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Amino acid metabolism in muscle and in the whole body of man before and after ingestion of a single mixed meal

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Increase in anterior tibialis muscle protein synthesis in healthy man during mixed amino acid infusion: studies of incorporation of [1-13C]leucine.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Skeletal muscle atrophy in old rats: differential changes in the three fiber types

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Role of leucine and other amino acids in regulating protein metabolism in vivo.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Leucine. A possible regulator of protein turnover in muscle

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Influence of amino acid availability on protein turnover in perfused skeletal muscle

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1819434

Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats

25 August 2018

1 reference

12 December 2020

Effect of amino acids alone or with insulin on muscle and liver protein synthesis in adult and old rats

1 reference

12 December 2020

Leucine incorporation into mixed skeletal muscle protein in humans

1 reference

12 December 2020

Leucine-supplemented meal feeding for ten days beneficially affects postprandial muscle protein synthesis in old rats

1 reference

12 December 2020

Pulse protein feeding pattern restores stimulation of muscle protein synthesis during the feeding period in old rats

1 reference

12 December 2020

The effect of leucine infusion on substrate flux across the human forearm

1 reference

12 December 2020

The significance of sarcopenia in old age

1 reference

12 December 2020

Altered response of protein synthesis to nutritional state and endurance training in old rats

1 reference

12 December 2020

The adult decline in lean body mass

1 reference

12 December 2020

Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction

1 reference

12 December 2020

Leucine supplementation has an anabolic effect on proteins in rabbit skin wound and muscle

1 reference

12 December 2020

Stimulation of in vitro rat muscle protein synthesis by leucine decreases with age

1 reference

12 December 2020

Involvement of food intake and amino acid catabolism in the branched-chain amino acid antagonism in chicks

1 reference

12 December 2020

Postprandial stimulation of muscle protein synthesis in old rats can be restored by a leucine-supplemented meal

1 reference

12 December 2020

Influence of leucine on arterial concentrations and regional exchange of amino acids in healthy subjects

1 reference

12 December 2020

Recovery of 13C in breath from NaH13CO3 infused by gut and vein: effect of feeding

1 reference

12 December 2020

Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids

1 reference

12 December 2020

10.1113/JPHYSIOL.2006.110742

Identifiers

DOI

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16 June 2018

0 references

1 reference

16 June 2018