(Q55054703)

16 June 2018

title

L-plastin phosphorylation: a novel target for the immunosuppressive drug dexamethasone in primary human T cells. (English)

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16 June 2018

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Guido H Wabnitz

1

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16 June 2018

Felix Michalke

2

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16 June 2018

Christoph Stober

3

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16 June 2018

Henning Kirchgessner

4

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16 June 2018

Beate Jahraus

5

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16 June 2018

Dick J H van den Boomen

6

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16 June 2018

Yvonne Samstag

7

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16 June 2018

language of work or name

English

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publication date

19 September 2011

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16 June 2018

European Journal of Immunology

published in

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16 June 2018

volume

41

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16 June 2018

issue

11

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16 June 2018

page(s)

3157-3169

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16 June 2018

Three-dimensional segregation of supramolecular activation clusters in T cells

cites work

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

The immunological synapse: a molecular machine controlling T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

T-cell activation through immunological synapses and kinapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Sustained LFA‐1 cluster formation in the immune synapse requires the combined activities of L‐plastin and calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

The actin cytoskeleton in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Costimulation induced phosphorylation of L-plastin facilitates surface transport of the T cell activation molecules CD69 and CD25

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Phosphorylation on Ser5 increases the F-actin-binding activity of L-plastin and promotes its targeting to sites of actin assembly in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Cofilin peptide homologs interfere with immunological synapse formation and T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Actin cytoskeletal dynamics in T lymphocyte activation and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Single-cell analyses reveal two defects in peptide-specific activation of naive T cells from aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Immune synapse formation determines interaction forces between T cells and antigen-presenting cells measured by atomic force microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Tuning immune responses: diversity and adaptation of the immunological synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

The actin-bundling protein L-plastin dissociates CCR7 proximal signaling from CCR7-induced motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

T cell antigen receptor signaling and immunological synapse stability require myosin IIA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Dexamethasone alters rapidly actin polymerization dynamics in human endometrial cells: evidence for nongenomic actions involving cAMP turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Glucocorticoid stabilization of actin filaments: a possible mechanism for inhibition of corticotropin release

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Mifepristone (RU486): a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Glucocorticoids attenuate T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Glucocorticoid-mediated inhibition of Lck modulates the pattern of T cell receptor-induced calcium signals by down-regulating inositol 1,4,5-trisphosphate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Immune complex-induced integrin activation and L-plastin phosphorylation require protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Dexamethasone suppresses antigen-induced activation of phosphatidylinositol 3-kinase and downstream responses in mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Actin-bundling protein L-plastin regulates T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Mitochondrial translocation of oxidized cofilin induces caspase-independent necrotic-like programmed cell death of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

Impairment of T cell interactions with antigen-presenting cells by immunosuppressive drugs reveals involvement of calcineurin and NF-κB in immunological synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

7 January 2021

Live-cell dynamics and the role of costimulation in immunological synapse formation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

7 January 2021

The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

7 January 2021

Oxidation of cofilin mediates T cell hyporesponsiveness under oxidative stress conditions

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

7 January 2021

Phosphatidylinositol 3-kinase functions as a Ras effector in the signaling cascade that regulates dephosphorylation of the actin-remodeling protein cofilin after costimulation of untransformed human T lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

7 January 2021

p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

7 January 2021

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201041366

7 January 2021

Identifiers

DOI

10.1002/EJI.201041366

1 reference

16 June 2018

1 reference

16 June 2018