(Q55068778)

16 June 2018

title

Cell biology. Making sense of amino acid sensing. (English)

1 reference

16 June 2018

1 reference

Robert T Abraham

1

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16 June 2018

language of work or name

English

0 references

publication date

1 January 2015

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16 June 2018

number of pages

2

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based on heuristic

inferred from page(s)

published in

Science

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16 June 2018

volume

347

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16 June 2018

issue

6218

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16 June 2018

page(s)

128-129

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16 June 2018

mTOR: from growth signal integration to cancer, diabetes and ageing

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

Amino acid signalling upstream of mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

Regulation of TORC1 by Rag GTPases in nutrient response

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

Rab1A is an mTORC1 activator and a colorectal oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

Metabolism. Differential regulation of mTORC1 by leucine and glutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

The solute carrier families have a remarkably long evolutionary history with the majority of the human families present before divergence of Bilaterian species

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4570

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAA4570

1 reference

16 June 2018

PubMed ID

25574008

1 reference

16 June 2018