(Q55093431)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

title

In vivo demonstration of an active tumor pretargeting approach with peptide nucleic acid bioconjugates as complementary system (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Holger Stephan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Kristof Zarschler

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Jörg Steinbach

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Gilles Gasser

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

author name string

Anna Leonidova

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Christian Foerster

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Maik Schubert

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Hans-Jürgen Pietzsch

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Ralf Bergmann

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

publication date

17 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

page(s)

5601-5616

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

29 March 2020

copyright license

start time

17 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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22 June 2018

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Cytotoxic properties of radionuclide-conjugated Cetuximab without and in combination with external irradiation in head and neck cancer cells in vitro.

22 June 2018

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Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential

22 June 2018

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Antisense peptide nucleic acid-functionalized cationic nanocomplex for in vivo mRNA detection

22 June 2018

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The inverse electron demand Diels-Alder click reaction in radiochemistry

22 June 2018

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Matching chelators to radiometals for radiopharmaceuticals

22 June 2018

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High-yield production of functional soluble single-domain antibodies in the cytoplasm of Escherichia coli.

22 June 2018

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Nucleic Acid-directed Self-assembly of Multifunctional Gold Nanoparticle Imaging Agents.

22 June 2018

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Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5

22 June 2018

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Epidermal growth factor receptor targeting in cancer: a review of trends and strategies.

22 June 2018

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Targeting the ERBB family in cancer: couples therapy

22 June 2018

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Development of an imaging-guided CEA-pretargeted radionuclide treatment of advanced colorectal cancer: first clinical results

22 June 2018

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Improvement of radioimmunotherapy using pretargeting

22 June 2018

1 reference

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High affinity γPNA sandwich hybridization assay for rapid detection of short nucleic acid targets with single mismatch discrimination.

22 June 2018

1 reference

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General overview of radioimmunotherapy of solid tumors

22 June 2018

1 reference

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Tumour targeting with radiometals for diagnosis and therapy

22 June 2018

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Designing PEGylated therapeutic molecules: advantages in ADMET properties

22 June 2018

1 reference

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Inactivation of HNSCC cells by 90Y-labeled cetuximab strictly depends on the number of induced DNA double-strand breaks

22 June 2018

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Radiometals for combined imaging and therapy

22 June 2018

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Advances in immuno-positron emission tomography: antibodies for molecular imaging in oncology

22 June 2018

1 reference

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Radiolabeled antibodies for cancer imaging and therapy

22 June 2018

1 reference

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Cellular and molecular properties of (90)Y-labeled cetuximab in combination with radiotherapy on human tumor cells in vitro

22 June 2018

1 reference

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Pretargeted molecular imaging and radioimmunotherapy

22 June 2018

1 reference

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Using antibodies to target cancer therapeutics

22 June 2018

1 reference

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Estimation of binding constants of peptide nucleic acid and secondary-structured DNA by affinity capillary electrophoresis.

22 June 2018

1 reference

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A comparison of in vitro methods for determining the membrane receptor expression in cell lines.

22 June 2018

1 reference

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Pretargeting: taking an alternate route for localizing radionuclides

22 June 2018

1 reference

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90Y labeled phosphorodiamidate morpholino oligomer for pretargeting radiotherapy

22 June 2018

1 reference

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Immuno-imaging using nanobodies

22 June 2018

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Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility

22 June 2018

1 reference

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Cancer radioimmunotherapy

22 June 2018

1 reference

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Comparing the epidermal growth factor interaction with four different cell lines: intriguing effects imply strong dependency of cellular context

22 June 2018

1 reference

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Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab

22 June 2018

1 reference

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A preclinical 188Re tumor therapeutic investigation using MORF/cMORF pretargeting and an antiTAG-72 antibody CC49.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Poly(ethylene glycol) in drug delivery: pros and cons as well as potential alternatives

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

EGFR signaling and drug discovery.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Radioimmunotherapy of lymphoma: Bexxar and Zevalin

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Cetuximab: from bench to bedside.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

ErbB receptors and signaling pathways in cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

PNA-PEG modified silicon platforms as functional bio-interfaces for applications in DNA microarrays and biosensors

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Monitoring gene therapy by external imaging of mRNA: pilot study on murine erythropoietin.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Bispecific antibody pretargeting of radionuclides for immuno single-photon emission computed tomography and immuno positron emission tomography molecular imaging: an update

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

An improved method for covalently conjugating morpholino oligomers to antitumor antibodies

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Receptor tyrosine kinases: mechanisms of activation and signaling

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Elimination mechanisms of therapeutic monoclonal antibodies

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Antibody pretargeting advances cancer radioimmunodetection and radioimmunotherapy.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Tumor-targeting peptide-PNA-peptide chimeras for imaging overexpressed oncogene mRNAs.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

PEGylation, successful approach to drug delivery

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Improving the delivery of radionuclides for imaging and therapy of cancer using pretargeting methods

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Cetuximab: an epidermal growth factor receptor chemeric human-murine monoclonal antibody

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Antisense imaging: And miles to go before we sleep?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Selective inhibition of inducible cyclo-oxygenase-2 expression by antisense peptide nucleic acids in intact murine macrophages

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

The ErbB receptors and their role in cancer progression.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Effect of pegylation on pharmaceuticals

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Improving the efficacy of antibody-based cancer therapies

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Pretargeted adjuvant radioimmunotherapy with yttrium-90-biotin in malignant glioma patients: a pilot study

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Cell signaling by receptor tyrosine kinases

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Phase II trial of yttrium-90-DOTA-biotin pretargeted by NR-LU-10 antibody/streptavidin in patients with metastatic colon cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

NHS-MAS3: a bifunctional chelator alternative to NHS-MAG3.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Morpholino antisense oligomers: design, preparation, and properties

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Epidermal growth factor receptor gene expression, protein kinase activity, and terminal differentiation of human malignant epidermal cells.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Delivery of novel therapeutic agents in tumors: physiological barriers and strategies

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Potential of a Cetuximab-based radioimmunotherapy combined with external irradiation manifests in a 3-D cell assay.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Preparation, 99mTc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2'-dipicolylamine

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Epidermal growth factor competes with EGF receptor inhibitors to induce cell death in EGFR-overexpressing tumor cells

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

PNA conjugated to high-molecular weight poly(ethylene glycol): synthesis and properties.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Patient-specific dosimetry of pretargeted radioimmunotherapy using CC49 fusion protein in patients with gastrointestinal malignancies.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Cetuximab: an IgG(1) monoclonal antibody for the treatment of epidermal growth factor receptor-expressing tumours

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

The discovery of receptor tyrosine kinases: targets for cancer therapy

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Investigations of 99mTc morpholino pretargeting in mice

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Tumor pretargeting in mice using (99m)Tc-labeled morpholino, a DNA analog.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Initial investigations of 99mTc-labeled morpholinos for radiopharmaceutical applications.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Specific recognition of antibody-oligonucleotide conjugates by radiolabeled antisense nucleotides: a novel approach for two-step radioimmunotherapy of cancer

13 August 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5SC00951K

A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules: Synthesis of [99mTc(OH2)3(CO)3]+from [99mTcO4]-in Aqueous Solution and Its Reaction with a Bifunctional Ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5SC00951K

Targeting, toxicity, and efficacy of 2-step, pretargeted radioimmunotherapy using a chimeric bispecific antibody and 131I-labeled bivalent hapten in a phase I optimization clinical trial

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949856

Antibodies against metal chelates

30 November 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5SC00951K

Preparation of Metal-Containing Peptide Nucleic Acid Bioconjugates on the Solid Phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5SC00951K

Synthesis of organometallic PNA oligomers by click chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5SC00951K

Synthesis of Stable Peptide Nucleic Acid-Modified Gold Nanoparticles and their Assembly onto Gold Surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5SC00951K

Investigations of avidin and biotin for imaging applications

21 January 2018

1 reference

12 December 2020

Bispecific monoclonal antibody-mediated targeting of an indium-111-labeled DTPA dimer to primary colorectal tumors: pharmacokinetics, biodistribution, scintigraphy and immune response

1 reference

12 December 2020

In vivo hybridization of technetium-99m-labeled peptide nucleic acid (PNA)

1 reference

12 December 2020

Bivalent hapten-bearing peptides designed for iodine-131 pretargeted radioimmunotherapy

1 reference

12 December 2020

Therapy for colon carcinoma xenografts with bispecific antibody-targeted, iodine-131-labeled bivalent hapten

1 reference

12 December 2020

Pretargeting using peptide nucleic acid

1 reference

12 December 2020

Radioimmunotherapy in medullary thyroid cancer using bispecific antibody and iodine 131-labeled bivalent hapten: preliminary results of a phase I/II clinical trial

1 reference

12 December 2020

Recombinant antibody toxins specific for ErbB2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumor regression in vivo

1 reference

12 December 2020

Pretargeting with amplification using polymeric peptide nucleic acid

1 reference

12 December 2020

The influence of chain length and base sequence on the pharmacokinetic behavior of 99mTc-morpholinos in mice

1 reference

12 December 2020

A universal pretargeting system for cancer detection and therapy using bispecific antibody

1 reference

12 December 2020

Synthesis and chromatography-free purification of PNA-PEO conjugates for the functionalisation of gold sensors

1 reference

12 December 2020

Identifiers

DOI

10.1039/C5SC00951K

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29861898%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

PubMed publication ID

29861898

1 reference