(Q55097241)

19 June 2018

title

Extracellular vesicles in mesenchymal stromal cells: A novel therapeutic strategy for stroke. (English)

1 reference

19 June 2018

main subject

extracellular vesicle

1 reference

Yingchen Li

1

1 reference

19 June 2018

Qilai Cheng

2

1 reference

19 June 2018

Guoheng Hu

3

1 reference

19 June 2018

Tianhao Deng

4

1 reference

19 June 2018

Qimei Wang

5

1 reference

19 June 2018

Jianda Zhou

6

1 reference

19 June 2018

Xinping Su

7

1 reference

19 June 2018

publication date

22 March 2018

1 reference

19 June 2018

Experimental and Therapeutic Medicine

published in

1 reference

19 June 2018

volume

15

1 reference

19 June 2018

issue

5

1 reference

19 June 2018

page(s)

4067-4079

1 reference

19 June 2018

Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles.

cites work

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White Matter Repair After Extracellular Vesicles Administration in an Experimental Animal Model of Subcortical Stroke

22 June 2018

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Secondary Release of Exosomes From Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery After Stroke in Rats Treated With Exosomes Harvested From MicroRNA 133b-Overexpressing Multipotent Mesenchymal Stro

22 June 2018

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Clinical Outcomes of Transplanted Modified Bone Marrow-Derived Mesenchymal Stem Cells in Stroke: A Phase 1/2a Study

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Analyses of Endothelial Cells and Endothelial Progenitor Cells Released Microvesicles by Using Microbead and Q-dot Based Nanoparticle Tracking Analysis.

22 June 2018

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22 June 2018

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Extracellular Vesicles: A New Frontier in Biomarker Discovery for Non-Alcoholic Fatty Liver Disease

22 June 2018

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Mononuclear Phagocyte-Derived Microparticulate Caspase-1 Induces Pulmonary Vascular Endothelial Cell Injury

22 June 2018

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22 June 2018

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The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration

22 June 2018

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Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

22 June 2018

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Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression

22 June 2018

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High-yield isolation of extracellular vesicles using aqueous two-phase system

22 June 2018

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Factors governing the immunosuppressive effects of multipotent mesenchymal stromal cells in vitro

22 June 2018

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Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects

22 June 2018

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Biological properties of extracellular vesicles and their physiological functions.

22 June 2018

1 reference

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AKI Recovery Induced by Mesenchymal Stromal Cell-Derived Extracellular Vesicles Carrying MicroRNAs

22 June 2018

1 reference

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Novel clinical uses for cord blood derived mesenchymal stromal cells

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Emerging picture of the distinct traits and functions of microvesicles and exosomes

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Differential fates of biomolecules delivered to target cells via extracellular vesicles.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Implantation of human umbilical cord mesenchymal stem cells for ischemic stroke: perspectives and challenges

22 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Microvesicles: ubiquitous contributors to infection and immunity

22 June 2018

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Human saliva-derived exosomes: comparing methods of isolation

22 June 2018

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Exosomes/miRNAs as mediating cell-based therapy of stroke

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

22 June 2018

1 reference

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Therapeutic applications of extracellular vesicles: clinical promise and open questions

22 June 2018

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Endothelial and cancer cells interact with mesenchymal stem cells via both microparticles and secreted factors

22 June 2018

1 reference

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Mesenchymal stem cell-derived microparticles: a promising therapeutic strategy

22 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

MicroRNA and mRNA cargo of extracellular vesicles from porcine adipose tissue-derived mesenchymal stem cells

22 June 2018

1 reference

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Extracellular vesicles as therapeutic tools in cardiovascular diseases

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Extracellular vesicles as modulators of cell-to-cell communication in the healthy and diseased brain

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

MicroRNAs transported by exosomes in body fluids as mediators of intercellular communication in cancer.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Extracellular Vesicles in Multiple Sclerosis: What are They Telling Us?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Stem cell-based therapies for ischemic stroke

22 June 2018

1 reference

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Meta-analysis of preclinical studies of mesenchymal stromal cells for ischemic stroke.

22 June 2018

1 reference

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Exosomes derived from mesenchymal stem cells.

22 June 2018

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The origin, function and diagnostic potential of extracellular microRNA in human body fluids

22 June 2018

1 reference

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Conditioned medium of human adipose-derived mesenchymal stem cells mediates protection in neurons following glutamate excitotoxicity by regulating energy metabolism and GAP-43 expression

22 June 2018

1 reference

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The role of astrocytes in mediating exogenous cell-based restorative therapy for stroke

22 June 2018

1 reference

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Exosomes: a novel pathway of local and distant intercellular communication that facilitates the growth and metastasis of neoplastic lesions

22 June 2018

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Paracrine mechanisms of proliferative, anti-apoptotic and anti-inflammatory effects of mesenchymal stromal cells in models of acute organ injury

22 June 2018

1 reference

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Mesenchymal stromal cells: sensors and switchers of inflammation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Standardization of sample collection, isolation and analysis methods in extracellular vesicle research

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes

22 June 2018

1 reference

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Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome-enriched extracellular particles

22 June 2018

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22 June 2018

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Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth

22 June 2018

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Embryonic stem cell-derived microvesicles induce gene expression changes in Müller cells of the retina

22 June 2018

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Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

22 June 2018

1 reference

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Feasibility of delivering mesenchymal stem cells via catheter to the proximal end of the lesion artery in patients with stroke in the territory of the middle cerebral artery

22 June 2018

1 reference

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Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells

22 June 2018

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Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome

22 June 2018

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Therapeutic potential of mesenchymal stem cell-derived microvesicles.

22 June 2018

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Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery

22 June 2018

1 reference

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Role of exosomes/microvesicles in the nervous system and use in emerging therapies

22 June 2018

1 reference

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Classification, functions, and clinical relevance of extracellular vesicles

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Autologous mesenchymal stem cells in chronic stroke

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Endothelial microparticles: missing link in endothelial dysfunction?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Methodology for isolation, identification and characterization of microvesicles in peripheral blood

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Mesenchymal stem cells: angels or demons?

22 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

The MSC: an injury drugstore

22 June 2018

1 reference

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Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Human umbilical mesenchymal stem cells promote recovery after ischemic stroke

22 June 2018

1 reference

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Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

22 June 2018

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Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs

22 June 2018

1 reference

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Malignant tumor formation after transplantation of short-term cultured bone marrow mesenchymal stem cells in experimental myocardial infarction and diabetic neuropathy.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Endovascular stroke treatment today.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Overcoming limitations of microparticle measurement by flow cytometry

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Microparticles: protagonists of a novel communication network for intercellular information exchange

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

The science of stroke: mechanisms in search of treatments

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Membrane vesicles as conveyors of immune responses

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Fate of culture-expanded mesenchymal stem cells in the microvasculature: in vivo observations of cell kinetics

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Isolation and characterization of exosomes from cell culture supernatants and biological fluids

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

22 June 2018

1 reference

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Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Pluripotency of mesenchymal stem cells derived from adult marrow

22 June 2018

1 reference

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Multilineage potential of adult human mesenchymal stem cells

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Exosomes as new diagnostic tools in CNS diseases.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Intranasal delivery of bone marrow mesenchymal stem cells improved neurovascular regeneration and rescued neuropsychiatric deficits after neonatal stroke in rats

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Bone marrow mesenchymal stem cell-derived microvesicles protect rat pheochromocytoma PC12 cells from glutamate-induced injury via a PI3K/Akt dependent pathway.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Light-controlled astrocytes promote human mesenchymal stem cells toward neuronal differentiation and improve the neurological deficit in stroke rats.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Stem cell therapy: a clinical trial of stroke

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Proteomic analysis of TNF-α-activated endothelial cells and endothelial microparticles

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Microvesicles derived from mesenchymal stem cells: potent organelles for induction of tolerogenic signaling.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Conversion potential of marrow cells into lung cells fluctuates with cytokine-induced cell cycle.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920496

Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment

13 August 2018

1 reference

12 December 2020

Autologous mesenchymal stem cell transplantation in stroke patients

1 reference

12 December 2020

Cell biology: The ins and outs of exosomes

1 reference

12 December 2020

The emerging role of microvesicles in cellular therapies for organ/tissue regeneration

1 reference

12 December 2020

Identifiers

DOI

10.3892/ETM.2018.5993

1 reference

19 June 2018

PMC publication ID

5920496

1 reference

19 June 2018

PubMed publication ID

29725359

1 reference

19 June 2018