(Q55217580)

English

Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54)

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9023163)

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Statements

biological process

1 reference

8 July 2022

Insulin processing

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9023163

1 reference

8 July 2022

6x2xHC-INS(25-56):4xHC-INS(57-110):2xZn2+:1xCa2+ [secretory granule lumen]

1

object has role

1 reference

8 July 2022

2

object has role

1 reference

8 July 2022

6x2xHC-INS(25-54):4xHC-INS(57-110):2xZn2+:1xCa2+ [secretory granule lumen]

1

object has role

1 reference

8 July 2022

CPE:Zn2+ [secretory granule membrane]

1

object has role

1 reference

8 July 2022

Direct identification of prohormone conversion site in insulin-secreting cells

1 reference

8 July 2022

Missense polymorphism in the human carboxypeptidase E gene alters enzymatic activity.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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