(Q55297874)

English

Rebuttal of "Flawed Experimental Design Reveals the Need for Guidelines Requiring Appropriate Positive Controls in Endocrine Disruption Research" by (Vom Saal 2010).

scientific article published on 5 March 2010

In more languages

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

Rebuttal of "Flawed Experimental Design Reveals the Need for Guidelines Requiring Appropriate Positive Controls in Endocrine Disruption Research" by (Vom Saal 2010). (English)

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

author name string

Leon Earl Gray

1

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

Bryce Ryan

2

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

Andrew K Hotchkiss

3

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

Kevin M Crofton

4

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

publication date

5 March 2010

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

Toxicological Sciences

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

115

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

2

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

614-620

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

In utero and lactational exposure to bisphenol A, in contrast to ethinyl estradiol, does not alter sexually dimorphic behavior, puberty, fertility, and anatomy of female LE rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

NTP-CERHR monograph on the potential human reproductive and developmental effects of bisphenol A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Early-onset endocrine disruptor-induced prostatitis in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

NTP-CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Estradiol and the developing brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Collapse of a fish population after exposure to a synthetic estrogen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Predicted exposures to steroid estrogens in U.K. rivers correlate with widespread sexual disruption in wild fish populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Genetic determination of susceptibility to estrogen-induced mammary cancer in the ACI rat: mapping of Emca1 and Emca2 to chromosomes 5 and 18.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Estrogen receptors as targets for drug development for breast cancer, osteoporosis and cardiovascular diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Inhibition of Testicular Steroidogenesis by the Xenoestrogen Bisphenol A Is Associated with Reduced Pituitary Luteinizing Hormone Secretion and Decreased Steroidogenic Enzyme Gene Expression in Rat Leydig Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Bisphenol A: findings of a multigenerational rat study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Bisphenol A is released from used polycarbonate animal cages into water at room temperature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Bisphenol a exposure causes meiotic aneuploidy in the female mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Analysis of the molecular mechanisms of human estrogen receptors alpha and beta reveals differential specificity in target promoter regulation by xenoestrogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Tissue-specific estrogenic response and molecular mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

In utero exposure to low doses of bisphenol A lead to long-term deleterious effects in the vagina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Diversity in the mechanisms of gene regulation by estrogen receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual di

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

The fungicide procymidone alters sexual differentiation in the male rat by acting as an androgen-receptor antagonist in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

90-day feeding and one-generation reproduction study in Crl:CD BR rats with 17 beta-estradiol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Estrogens and the genetic control of tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

The use of estrogens as postcoital contraceptive agents. Clinical effectiveness and potential mode of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Methoxychlor induces estrogen-like alterations of behavior and the reproductive tract in the female rat and hamster: effects on sex behavior, running wheel activity, and uterine morphology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Alteration of behavioral sex differentiation by exposure to estrogenic compounds during a critical neonatal period: effects of zearalenone, methoxychlor, and estradiol in hamsters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Effects of low subchronic doses of methoxychlor on the rat hypothalamic-pituitary reproductive axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

3 July 2018

Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Genistein and ethinyl estradiol dietary exposure in multigenerational and chronic studies induce similar proliferative lesions in mammary gland of male Sprague-Dawley rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Two-generation reproductive toxicity study of dietary bisphenol A in CD-1 (Swiss) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Two-generation reproductive toxicity evaluation of dietary 17beta-estradiol (E2; CAS No. 50-28-2) in CD-1 (Swiss) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Developmental effects of ethinylestradiol on reproductive organs of female mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Localization of Eutr2, a locus controlling susceptibility to DES-induced uterine inflammation and pyometritis, to RNO5 using a congenic rat strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Genetic mapping of Eutr1, a locus controlling E2-induced pyometritis in the Brown Norway rat, to RNO5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Ethinylestradiol and testosterone have divergent effects on circulating IGF system components in adolescents with constitutional tall stature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Bisphenol-A, an environmental contaminant that acts as a thyroid hormone receptor antagonist in vitro, increases serum thyroxine, and alters RC3/neurogranin expression in the developing rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Studies on mating behavior in the androgen-sterilized female rat in relation to the hypothalamic regulation of sexual behaviour.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Normal sexual development of two strains of rat exposed in utero to low doses of bisphenol A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Gene expression profile induced by 17alpha-ethynyl estradiol, bisphenol A, and genistein in the developing female reproductive system of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Rat two-generation reproductive toxicity study of bisphenol A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

In utero exposure to bisphenol A alters the development and tissue organization of the mouse mammary gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Estrogenic activity of octylphenol, nonylphenol, bisphenol A and methoxychlor in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

The effects of 4-nonylphenol in rats: a multigeneration reproduction study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Normal reproductive organ development in CF-1 mice following prenatal exposure to bisphenol A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

The estrogenic and antiandrogenic pesticide methoxychlor alters the reproductive tract and behavior without affecting pituitary size or LH and prolactin secretion in male rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Genetic differences in estrogen-induced deoxyribonucleic acid synthesis in the rat pituitary: correlations with pituitary tumor susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Reduction of body height in tall girls by estrogen treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6002156

12 August 2018

Effect of prenatal treatment with ethinyl estradiol on the mouse uterus and ovary

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen treatment of tall girls: dose dependency of effects on subsequent growth and IGF-I levels in blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leydig cell hyperplasia in fetal mice treated transplacentally with ethinyl estradiol

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated differentiation in seminiferous tubules of fetal mice prenatally exposed to ethinyl estradiol

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovarian follicular cell hyperplasia in fetal mice treated transplacentally with ethinyl estradiol

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ethinyl estradiol on the differentiation of mouse fetal testis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gonadal dysgenesis induced by prenatal exposure to ethinyl estradiol in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The after-pill. Experiences of 1000 women with postcoital administration of high estrogen doses

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex differences in taste preference for glucose and saccharin solutions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovariectomized Sprague-Dawley and Long-Evans rats release prolactin differently in response to estrogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ethinyl estradiol on development of mouse fetuses

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative trait loci for estrogen-dependent pituitary tumor growth in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal reproductive organ development in Wistar rats exposed to bisphenol A in the drinking water

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uterotrophic activity of bisphenol A in the immature mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DES action in the thymus: inhibition of cell proliferation and genetic variation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of significant alteration in the prostate or testis of F344 rat offspring after transplacental and lactational exposure to bisphenol A

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ESTROGEN ADMINISTERED NEONATALLY AFFECTS ADULT SEXUAL BEHAVIOR IN MALE AND FEMALE RATS

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic mapping of loci controlling diethylstilbestrol-induced thymic atrophy in the Brown Norway rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/29910598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/TOXSCI/KFQ073

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/6002156

ResearchGate publication ID

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