(Q55470661)

12 July 2018

title

Linking DNA damage to medulloblastoma tumorigenesis in patched heterozygous knockout mice. (English)

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12 July 2018

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8

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12 July 2018

Anna Saran

10

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12 July 2018

author name string

S Pazzaglia

1

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12 July 2018

M Tanori

2

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12 July 2018

M Mancuso

3

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12 July 2018

S Rebessi

4

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12 July 2018

S Leonardi

5

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12 July 2018

V Di Majo

6

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12 July 2018

V Covelli

7

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12 July 2018

H Hahn

9

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12 July 2018

language of work or name

English

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publication date

1 February 2006

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12 July 2018

published in

Oncogene

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12 July 2018

volume

25

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12 July 2018

page(s)

1165-1173

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12 July 2018

issue

8

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12 July 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209032

exact match

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cites work

Effects of low-level x-irradiation on cat cerebella at different postnatal intervals. I. Quantitative evaluation of morphological changes

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The Rb2/p130 gene product is a nuclear protein whose phosphorylation is cycle regulated

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7 January 2021

Medulloblastoma growth inhibition by hedgehog pathway blockade

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7 January 2021

Loss of heterozygosity occurs via mitotic recombination in Trp53+/- mice and associates with mammary tumor susceptibility of the BALB/c strain

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7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

Unbalanced overexpression of the mutant allele in murine Patched mutants

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

Radiation-induced DNA strand breaks and cell pycnosis in the developing rat cerebellum.

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7 January 2021

Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner.

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7 January 2021

The role of the insulin-like growth factors in the central nervous system

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7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

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7 January 2021

Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons.

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7 January 2021

Altered neural cell fates and medulloblastoma in mouse patched mutants

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7 January 2021

Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma.

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7 January 2021

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

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7 January 2021

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

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7 January 2021

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

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7 January 2021

Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons.

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7 January 2021

Advances in the Diagnosis, Molecular Genetics, and Treatment of Pediatric Embryonal CNS Tumors

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7 January 2021

Basal cell carcinoma and its development: insights from radiation-induced tumors in Ptch1-deficient mice

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7 January 2021

High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1 heterozygous mice

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7 January 2021

Medulloblastoma: molecular genetics and animal models

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7 January 2021

Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

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7 January 2021

Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination

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7 January 2021

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

Extensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaks

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

The role of free radicals and p53 in neuron apoptosis in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

In vivo actions of insulin-like growth factor-I (IGF-I) on cerebellum development in transgenic mice: evidence that IGF-I increases proliferation of granule cell progenitors.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209032

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209032

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12 July 2018

Dimensions Publication ID

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1 reference

12 July 2018