Wikidata

(Q5572591)

English

Glycyl-tRNA synthetase 1

mammalian protein found in Homo sapiens

  • GARS1
  • GlyRS
  • ap4A synthetase
  • diadenosine tetraphosphate synthetase
  • GARS
  • AP-4-A synthetase
  • Charcot-Marie-Tooth neuropathy, neuronal type, D
  • Charcot-Marie-Tooth neuropathy 2D
  • glycine--tRNA ligase
  • glycine-tRNA ligase
In more languages

Statements

molecular function
glycine-tRNA ligase activity
determination method
IDA
IEA
IMP
TAS
8 references
retrieved
5 June 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
TAS
retrieved
5 June 2018
stated in
Compound heterozygosity for loss-of-function GARS variants results in a multisystem developmental syndrome that includes severe growth retardation
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IMP
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IEA
retrieved
5 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IEA
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IEA
retrieved
5 June 2018
stated in
Long-range structural effects of a Charcot-Marie-Tooth disease-causing mutation in human glycyl-tRNA synthetase
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IDA
retrieved
5 June 2018
stated in
Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IDA
retrieved
5 June 2018
stated in
Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IDA
glycine-tRNA ligase activity
determination method
IBA
IDA
IEA
IMP
TAS
9 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
TAS
retrieved
1 January 2018
stated in
Compound heterozygosity for loss-of-function GARS variants results in a multisystem developmental syndrome that includes severe growth retardation
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IMP
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IEA
retrieved
1 January 2018
stated in
Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IDA
retrieved
1 January 2018
stated in
Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IDA
retrieved
1 January 2018
stated in
Long-range structural effects of a Charcot-Marie-Tooth disease-causing mutation in human glycyl-tRNA synthetase
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41250&geneProductId=UniProtKB:P41250
determination method
IBA
glycine-tRNA ligase activity
determination method
IBA
IDA
IEA
IMP
8 references
retrieved
9 May 2019
stated in
Compound heterozygosity for loss-of-function GARS variants results in a multisystem developmental syndrome that includes severe growth retardation
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41250
determination method
IMP
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41250
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41250
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41250
determination method
IEA
retrieved
9 May 2019
stated in
Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41250
determination method
IDA
retrieved
9 May 2019
stated in
Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41250
determination method
IDA
retrieved
9 May 2019
stated in
Long-range structural effects of a Charcot-Marie-Tooth disease-causing mutation in human glycyl-tRNA synthetase
GOA
curator
UniProt
UniProt protein ID
P41250
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41250
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41250
determination method
IBA
cell component
biological process
Gene Atlas image
PBB GE GARS 208693 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
D006032
subject named as
Glycine-tRNA Ligase
0 references
PDB structure ID
 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q5572591&oldid=2022908138"