Wikidata

(Q5630986)

English

High mobility group AT-hook 2

mammalian protein found in Homo sapiens

  • High mobility group AT-hook protein 2
  • high-mobility group (nonhistone chromosomal) protein isoform I-C
  • HMGA2/KRT121P fusion
  • HMGA2
  • high mobility group protein HMGI-C
In more languages

Statements

molecular function
minor groove of adenine-thymine-rich DNA binding
determination method
IDA
TAS
IMP
7 references
retrieved
8 April 2019
stated in
Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
TAS
retrieved
8 April 2019
stated in
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IMP
retrieved
8 April 2019
stated in
High-level expression of DNA architectural factor HMGA2 and its association with nucleosomes in human embryonic stem cells
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
High mobility group A2 protein and its derivatives bind a specific region of the promoter of DNA repair gene ERCC1 and modulate its activity
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
DNA bending by the mammalian high-mobility group protein AT hook 2
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
cell component
nucleus
determination method
IDA
IEA
6 references
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52926&geneProductId=UniProtKB:P52926
determination method
IEA
retrieved
31 October 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52926&geneProductId=UniProtKB:P52926
determination method
IEA
retrieved
31 October 2017
stated in
A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52926&geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
31 October 2017
stated in
The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52926&geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
31 October 2017
stated in
High-level expression of DNA architectural factor HMGA2 and its association with nucleosomes in human embryonic stem cells
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52926&geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
31 October 2017
stated in
Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52926&geneProductId=UniProtKB:P52926
determination method
IDA
nucleus
determination method
HDA
IBA
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IEA
retrieved
8 April 2019
stated in
The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
High-level expression of DNA architectural factor HMGA2 and its association with nucleosomes in human embryonic stem cells
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IBA
retrieved
8 April 2019
stated in
Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
HDA
biological process
positive regulation of transcription, DNA-templated
determination method
IDA
IMP
6 references
retrieved
8 April 2019
stated in
DNA architectural factor and proto-oncogene HMGA2 regulates key developmental genes in pluripotent human embryonic stem cells
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IMP
retrieved
8 April 2019
stated in
Transactivation functions of the tumor-specific HMGA2/LPP fusion protein are augmented by wild-type HMGA2
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcription
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA
retrieved
8 April 2019
stated in
The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function
GOA
curator
UniProt
UniProt protein ID
P52926
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52926
determination method
IDA

Identifiers

MeSH descriptor ID
D025743
subject named as
HMGA2 Protein
0 references
 
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