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p-CD19:VAV binds PI3K and GRB2
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9606887)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
part of
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
exact match
https://identifiers.org/reactome:R-HSA-9606887
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
has part(s)
Growth factor receptor bound protein 2
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
p-CD19:VAV1 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
PIK3CD:PIK3R1 [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
CD19 Signalosome [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
cites work
Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursors
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontogeny
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
CD19 is a substrate of the antigen receptor-associated protein tyrosine kinase in human B cells.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
Binding of cytoplasmic proteins to the CD19 intracellular domain is high affinity, competitive, and multimeric
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
Systematic analysis of the role of CD19 cytoplasmic tyrosines in enhancement of activation in Daudi human B cells: clustering of phospholipase C and Vav and of Grb2 and Sos with different CD19 tyrosines
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
Tyrosine phosphorylation of CD19 in pre-B and mature B cells
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
Identifiers
Reactome ID
R-HSA-9606887
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9606887
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