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HIV-1 Nef: negative effector of Fas?
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title
HIV-1 Nef: negative effector of Fas?
(English)
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author name string
X N Xu
series ordinal
1
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G Screaton
series ordinal
2
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language of work or name
English
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publication date
May 2001
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published in
Nature Immunology
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volume
2
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issue
5
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page(s)
384-5
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cites work
Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes
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7 January 2021
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HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
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7 January 2021
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Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.
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reference URL
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7 January 2021
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Tat as one key to HIV-induced immune pathogenesis and Tat (correction of Pat) toxoid as an important component of a vaccine
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7 January 2021
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Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.
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Dual role of the HIV-1 vpr protein in the modulation of the apoptotic response of T cells.
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7 January 2021
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Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2
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7 January 2021
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Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
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7 January 2021
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The Nef protein of HIV-1 associates with rafts and primes T cells for activation
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7 January 2021
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Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
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7 January 2021
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HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization
1 reference
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https://api.crossref.org/works/10.1038%2F87682
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7 January 2021
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Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
1 reference
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7 January 2021
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HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.
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7 January 2021
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HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages
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7 January 2021
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Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain
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7 January 2021
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Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F87682
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7 January 2021
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Anti-apoptotic strategies of lymphotropic viruses
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F87682
retrieved
7 January 2021
based on heuristic
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Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation
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Crossref
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7 January 2021
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Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development
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7 January 2021
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Identifiers
DOI
10.1038/87682
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PubMed publication ID
11323689
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