(Q56894082)

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Functional role of evolutionarily highly conserved residues, N-glycosylation level and domains of the Leishmania miltefosine transporter-Cdc50 subunit

scientific article published on 01 April 2014

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24447089%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Functional role of evolutionarily highly conserved residues, N-glycosylation level and domains of the Leishmania miltefosine transporter-Cdc50 subunit (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24447089%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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based on heuristic

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Francisco Gamarro

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24447089%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Santiago Castanys

4

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Europe PubMed Central

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5 March 2020

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Sebastián García-Sánchez

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5 March 2020

María P Sánchez-Cañete

2

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5 March 2020

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1 April 2014

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5 March 2020

Biochemical Journal

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5 March 2020

459

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5 March 2020

1

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5 March 2020

83-94

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5 March 2020

Pumping lipids with P4-ATPases.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

P4 ATPases: flippases in health and disease

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Functions of phospholipid flippases

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Mechanism and significance of P4 ATPase-catalyzed lipid transport: lessons from a Na+/K+-pump.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Functional roles of Na,K-ATPase subunits

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Roles for the Drs2p-Cdc50p complex in protein transport and phosphatidylserine asymmetry of the yeast plasma membrane

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Phospholipid translocation and miltefosine potency require both L. donovani miltefosine transporter and the new protein LdRos3 in Leishmania parasites.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Endocytic recycling in yeast is regulated by putative phospholipid translocases and the Ypt31p/32p-Rcy1p pathway

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter Drs2p

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Critical role of the beta-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Isolation and characterization of novel mutations in CDC50, the non-catalytic subunit of the Drs2p phospholipid flippase.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Phosphatidylserine stimulation of Drs2p·Cdc50p lipid translocase dephosphorylation is controlled by phosphatidylinositol-4-phosphate.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Phospholipid flippases: building asymmetric membranes and transport vesicles.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Intracellular targeting signals and lipid specificity determinants of the ALA/ALIS P4-ATPase complex reside in the catalytic ALA alpha-subunit

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Crystal structure of the sodium-potassium pump at 2.4 A resolution

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Mapping functional interactions in a heterodimeric phospholipid pump

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Functional cloning of the miltefosine transporter. A novel P-type phospholipid translocase from Leishmania involved in drug resistance

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Human TMEM30a promotes uptake of antitumor and bioactive choline phospholipids into mammalian cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

CDC50A plays a key role in the uptake of the anticancer drug perifosine in human carcinoma cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Disruption of the lipid-transporting LdMT-LdRos3 complex in Leishmania donovani affects membrane lipid asymmetry but not host cell invasion

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Low plasma membrane expression of the miltefosine transport complex renders Leishmania braziliensis refractory to the drug

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Aberrant termination of reproduction-related TMEM30C transcripts in the hominoids.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

The Arabidopsis P4-ATPase ALA3 localizes to the golgi and requires a beta-subunit to function in lipid translocation and secretory vesicle formation.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

The roles of the Na,K-ATPase beta 1 subunit in pump sorting and epithelial integrity

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131318

21 January 2018

Identifiers

10.1042/BJ20131318

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24447089%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24447089%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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