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Antibody engineering
scientific article published on 01 August 1998
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Europe PubMed Central
PubMed publication ID
9729735
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
review article
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Europe PubMed Central
title
Antibody engineering
(English)
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Europe PubMed Central
PubMed publication ID
9729735
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
author name string
W Dall'Acqua
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1
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Europe PubMed Central
PubMed publication ID
9729735
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
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2
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Europe PubMed Central
PubMed publication ID
9729735
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
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English
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publication date
1 August 1998
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Europe PubMed Central
PubMed publication ID
9729735
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3 December 2019
published in
Current Opinion in Structural Biology
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Europe PubMed Central
PubMed publication ID
9729735
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
volume
8
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Europe PubMed Central
PubMed publication ID
9729735
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
issue
4
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Europe PubMed Central
PubMed publication ID
9729735
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
page(s)
443-450
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Europe PubMed Central
PubMed publication ID
9729735
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
cites work
Engineering antibodies for imaging and therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recombinant antibody fragments
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The state of antibody catalysis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
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The structural and functional basis of antibody catalysis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New protein engineering approaches to multivalent and bispecific antibody fragments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diabodies: small bispecific antibody fragments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phage display of combinatorial antibody libraries.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Designing and optimizing library selection strategies for generating high-affinity antibodies
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of human antibody repertoires in transgenic mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrabodies: turning the humoral immune system outside in for intracellular immunization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selectively infective phage (SIP) technology: a novel method for in vivo selection of interacting protein-ligand pairs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of binding interactions in an idiotope-antiidiotope protein-protein complex by double mutant cycles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
A hot spot of binding energy in a hormone-receptor interface
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
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Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
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Antibody fragment Fv4155 bound to two closely related steroid hormones: the structural basis of fine specificity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Humanized antibodies
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody humanization using monovalent phage display
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformational correction mechanisms aiding antigen recognition by a humanized antibody
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Replacing the complementarity-determining regions in a human antibody with those from a mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
"Diabodies": small bivalent and bispecific antibody fragments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High level secretion of a humanized bispecific diabody from Escherichia coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Remodeling domain interfaces to enhance heterodimer formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved tumour targeting by disulphide stabilized diabodies expressed in Pichia pastoris
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retargeting serum immunoglobulin with bispecific diabodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement recruitment using bispecific diabodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Single-chain Fv fragments of anti-neuraminidase antibody NC10 containing five- and ten-residue linkers form dimers and with zero-residue linker a trimer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Triabodies: single chain Fv fragments without a linker form trivalent trimers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The 2.0-A resolution crystal structure of a trimeric antibody fragment with noncognate VH-VL domain pairs shows a rearrangement of VH CDR3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bispecific monoclonal antibodies from hybrid hybridomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
'Knobs-into-holes' engineering of antibody CH3 domains for heavy chain heterodimerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stable heterodimers from remodeling the domain interface of a homodimer using a phage display library
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increasing the serum persistence of an IgG fragment by random mutagenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A natural antibody missing a cysteine in VH: consequences for thermodynamic stability and folding.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody scFv fragments without disulfide bonds made by molecular evolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The rational construction of an antibody against cystatin: lessons from the crystal structure of an artificial Fab fragment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative effects of mutations in a recombinant Fab on the kinetics of antigen binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformations of the third hypervariable region in the VH domain of immunoglobulins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stabilization of a recombinant Fv fragment by base-loop interconnection and V(H)-V(L) permutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High level Escherichia coli expression and production of a bivalent humanized antibody fragment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improving in vivo folding and stability of a single-chain Fv antibody fragment by loop grafting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phage display of a catalytic antibody to optimize affinity for transition-state analog binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engineered turns of a recombinant antibody improve its in vivo folding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of mutator cells as a means for increasing production levels of a recombinant antibody directed against Hepatitis B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection of linkers for a catalytic single-chain antibody using phage display technology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Importance of the linker in expression of single-chain Fv antibody fragments: optimisation of peptide sequence using phage display technology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro scanning saturation mutagenesis of an antibody binding pocket
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional antibody production using cell-free translation: effects of protein disulfide isomerase and chaperones.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of high affinity human antibodies directly from large synthetic repertoires.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct demonstration of MuSK involvement in acetylcholine receptor clustering through identification of agonist ScFv
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selectively-infective phage (SIP): a mechanistic dissection of a novel in vivo selection for protein-ligand interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Affinity and folding properties both influence the selection of antibodies with the selectively infective phage (SIP) methodology.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective phage infection mediated by epitope expression on F pilus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-selection of cognate antibody-antigen pairs by selectively-infective phages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Making chemistry selectable by linking it to infectivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An in vitro polysome display system for identifying ligands from very large peptide libraries
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro selection and evolution of functional proteins by using ribosome display
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An efficient route to human bispecific IgG.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980121-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0959-440X(98)80121-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9729735
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
PubMed publication ID
9729735
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9729735
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729735%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
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