(Q56973515)

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Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

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6 March 2020

Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma (English)

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6 March 2020

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Annamaria Brioli

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6 March 2020

Christopher P Wardell

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6 March 2020

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6 March 2020

Brian A. Walker

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6 March 2020

Gareth J Morgan

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6 March 2020

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L Melchor

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6 March 2020

A Murison

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6 March 2020

N E Potter

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6 March 2020

M F Kaiser

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R A Fryer

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6 March 2020

D C Johnson

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D B Begum

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6 March 2020

S Hulkki Wilson

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6 March 2020

G Vijayaraghavan

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6 March 2020

I Titley

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6 March 2020

F E Davies

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13 January 2014

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6 March 2020

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6 March 2020

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6 March 2020

1705-1715

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6 March 2020

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6 March 2020

https://scigraph.springernature.com/pub.10.1038/leu.2014.13

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Genetic variegation of clonal architecture and propagating cells in leukaemia

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Clonal competition with alternating dominance in multiple myeloma.

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Cancer as an evolutionary and ecological process

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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

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Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

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The life history of 21 breast cancers

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Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma.

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The patterns and dynamics of genomic instability in metastatic pancreatic cancer

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Cancer stem cells as 'units of selection'.

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Molecular pathogenesis of multiple myeloma and its premalignant precursor

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21 January 2018

The genetic architecture of multiple myeloma.

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21 January 2018

Initial genome sequencing and analysis of multiple myeloma

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21 January 2018

Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides

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21 January 2018

Minor clone provides a reservoir for relapse in multiple myeloma

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Temporal dissection of tumorigenesis in primary cancers

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Single-cell mutational profiling and clonal phylogeny in cancer

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21 January 2018

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.

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21 January 2018

Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.

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21 January 2018

Taking qPCR to a higher level: Analysis of CNV reveals the power of high throughput qPCR to enhance quantitative resolution

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ROCK: a breast cancer functional genomics resource.

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Characterization of a novel mouse model of multiple myeloma and its use in preclinical therapeutic assessment

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Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype

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Genome evolution during progression to breast cancer

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A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma

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Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

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Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes

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Clonal architecture of chronic myelomonocytic leukemias

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Targeting the BRAF V600E mutation in multiple myeloma

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Interferon regulatory factor 4 and 8 in B-cell development

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Control of autophagic cell death by caspase-10 in multiple myeloma

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21 January 2018

IRF4 addiction in multiple myeloma

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Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

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Lenalidomide efficacy in activated B-cell-like subtype diffuse large B-cell lymphoma is dependent upon IRF4 and cereblon expression

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21 January 2018

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.

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IRF4 mutations in chronic lymphocytic leukemia

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Intratumor heterogeneity: evolution through space and time

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Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma

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Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

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https://pubmed.ncbi.nlm.nih.gov/24480973

12 December 2020

based on heuristic

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A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

1 reference

https://pubmed.ncbi.nlm.nih.gov/24480973

12 December 2020

based on heuristic

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Genomic abnormalities in monoclonal gammopathy of undetermined significance

1 reference

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12 December 2020

based on heuristic

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Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24480973

12 December 2020

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10.1038/LEU.2014.13

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Europe PubMed Central

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6 March 2020

1 reference

Europe PubMed Central

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6 March 2020

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