(Q56985730)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21487632%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Computational evidence for the substrate-assisted catalytic mechanism of O-GlcNAcase. A DFT investigation (English)

1 reference

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28 January 2020

3

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28 January 2020

author name string

Andrea Bottoni

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21487632%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Gian Pietro Miscione

series ordinal

2

1 reference

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28 January 2020

language of work or name

English

0 references

publication date

13 April 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21487632%20AND%20SRC:MED&resulttype=core&format=json

Physical Chemistry Chemical Physics

28 January 2020

published in

1 reference

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28 January 2020

volume

13

1 reference

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28 January 2020

issue

20

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28 January 2020

page(s)

9568-9577

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21487632%20AND%20SRC:MED&resulttype=core&format=json

The protein kinase complement of the human genome

28 January 2020

cites work

1 reference

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Dynamic interplay between O-glycosylation and O-phosphorylation of nucleocytoplasmic proteins: alternative glycosylation/phosphorylation of THR-58, a known mutational hot spot of c-Myc in lymphomas, is regulated by mitogens

21 January 2018

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Alternative O-glycosylation/O-phosphorylation of the murine estrogen receptor beta.

21 January 2018

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Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins

21 January 2018

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Glycosylation of nucleocytoplasmic proteins: signal transduction and O-GlcNAc

21 January 2018

1 reference

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O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats

21 January 2018

1 reference

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Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats

21 January 2018

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Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain

21 January 2018

1 reference

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O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions

21 January 2018

1 reference

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Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation

21 January 2018

1 reference

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O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation

21 January 2018

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Analysis of nuclear pore protein p62 glycosylation

21 January 2018

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O-Linked N-Acetylglucosamine Is Upregulated in Alzheimer Brains

21 January 2018

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Glycosylation sites flank phosphorylation sites on synapsin I: O-linked N-acetylglucosamine residues are localized within domains mediating synapsin I interactions

21 January 2018

1 reference

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Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

21 January 2018

1 reference

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Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

21 January 2018

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Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability

21 January 2018

1 reference

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Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease

21 January 2018

1 reference

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Structural and sequence-based classification of glycoside hydrolases

21 January 2018

1 reference

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Molecular mechanisms of O-GlcNAcylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Structural analyses of enzymes involved in the O-GlcNAc modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Identification of Asp174 and Asp175 as the key catalytic residues of human O-GlcNAcase by functional analysis of site-directed mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Probing synergy between two catalytic strategies in the glycoside hydrolase O-GlcNAcase using multiple linear free energy relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Visualizing the reaction coordinate of an O-GlcNAc hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

A quantum mechanics/molecular mechanics study of the protein-ligand interaction of two potent inhibitors of human O-GlcNAcase: PUGNAc and NAG-thiazoline

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

The Amber biomolecular simulation programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Development and validation of a modular, extensible docking program: DOCK 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

A geometric approach to macromolecule-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Fast, efficient generation of high-quality atomic charges. AM1-BCC model: II. Parameterization and validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Development and testing of a general amber force field

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Density-functional thermochemistry. III. The role of exact exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Computational clues for a new mechanism in the glycosylase activity of the human DNA repair protein hOGG1. A generalized paradigm for purine-repairing systems?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

Computational evidence for the catalytic mechanism of glutaminyl cyclase. A DFT investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CP02308F

21 January 2018

Identifiers

DOI

10.1039/C0CP02308F

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21487632%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference