(Q57003687)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10455164%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

title

Novel mechanism of inhibition of elastase by beta-lactams is defined by two inhibitor crystal complexes (English)

1 reference

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11 December 2019

3

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11 December 2019

Sabine Flitsch

4

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11 December 2019

Nicholas J. Turner

5

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11 December 2019

Malcolm Walkinshaw

7

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11 December 2019

author name string

P Taylor

1

1 reference

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11 December 2019

V Anderson

2

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11 December 2019

K Loughran

6

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11 December 2019

language of work or name

English

0 references

publication date

1 August 1999

1 reference

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Journal of Biological Chemistry

11 December 2019

published in

1 reference

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11 December 2019

volume

274

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11 December 2019

issue

35

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11 December 2019

page(s)

24901-24905

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Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

11 December 2019

cites work

1 reference

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Mechanism of inhibition of LDL phospholipase A2 by monocyclic-beta-lactams. Burst kinetics and the effect of stereochemistry

21 January 2018

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Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor

21 January 2018

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Inhibition of cartilage degradation in rat collagen-induced arthritis but not adjuvant arthritis by the neutrophil elastase inhibitor MDL 101,146.

21 January 2018

1 reference

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Crystallographic study of a beta-lactam inhibitor complex with elastase at 1.84 A resolution

21 January 2018

1 reference

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Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex

21 January 2018

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AMoRe: an automated package for molecular replacement

21 January 2018

1 reference

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Mechanism of Inhibition of Human Leukocyte Elastase by .beta.-Lactams. 3. Use of Electrospray Ionization Mass Spectrometry and Two-Dimensional NMR Techniques To Identify .beta.-Lactam-Derived E-I Complexes

21 January 2018

1 reference

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Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution

21 January 2018

1 reference

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The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase

21 January 2018

1 reference

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Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase

21 January 2018

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Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors

21 January 2018

1 reference

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Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors

21 January 2018

1 reference

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Analogous inhibitors of elastase do not always bind analogously

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.35.24901

The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.35.24901

Crystallographic analysis of the inhibition of porcine pancreatic elastase by a peptidyl boronic acid: structure of a reaction intermediate

21 January 2018

1 reference

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Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.35.24901

Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.35.24901

Interaction of a Peptidomimetic Aminimide Inhibitor with Elastase

21 January 2018

1 reference

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Inhibition of TEM-2 beta-lactamase from Escherichia coli by clavulanic acid: observation of intermediates by electrospray ionization mass spectrometry.

21 January 2018

1 reference

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

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Mechanism of Inhibition of Human Leukocyte Elastase by .beta.-Lactams. 2. Stability, Reactivation Kinetics, and Products of .beta.-Lactam-Derived E-I Complexes

21 January 2018

1 reference

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Mechanism-based isocoumarin inhibitors for human leukocyte elastase. Effect of the 7-amino substituent and 3-alkoxy group in 3-alkoxy-7-amino-4-chloroisocoumarins on inhibitory potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.35.24901

Protease-antiprotease imbalance in the lungs of children with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.35.24901

X-ray diffraction analysis of the inhibition of porcine pancreatic elastase by a peptidyl trifluoromethylketone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.35.24901

Effect of the 7-amino substituent on the inhibitory potency of mechanism-based isocoumarin inhibitors for porcine pancreatic and human neutrophil elastases: a 1.85-A X-ray structure of the complex between porcine pancreatic elastase and 7-[(N-tosylp

21 January 2018

1 reference

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Inhibition of β-lactamase by clavulanate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.35.24901

21 January 2018

Identifiers

DOI

10.1074/JBC.274.35.24901

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10455164%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

1 reference