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cGAS and STING: At the intersection of DNA and RNA virus-sensing networks
scientific article published on 16 August 2018
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scholarly article
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Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
title
cGAS and STING: At the intersection of DNA and RNA virus-sensing networks
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
main subject
immunology
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molecular biology
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parasitology
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virology
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bites and stings
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author
Guoxin Ni
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
Zhe Ma
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
Blossom Damania
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
author name string
Guoxin Ni
series ordinal
1
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language of work or name
English
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publication date
16 August 2018
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stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
published in
PLOS Pathogens
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
volume
14
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
issue
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
page(s)
e1007148
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
copyright license
Creative Commons Attribution 4.0 International
start time
16 August 2018
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
STING-dependent translation inhibition restricts RNA virus replication.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Ubiquitination of STING at lysine 224 controls IRF3 activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Dengue virus activates cGAS through the release of mitochondrial DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
RIG-I-Mediated STING Upregulation Restricts Herpes Simplex Virus 1 Infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
The cGAS-STING Defense Pathway and Its Counteraction by Viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
STING: infection, inflammation and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Cells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Innate immune sensing and signaling of cytosolic nucleic acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Structural mechanism of cytosolic DNA sensing by cGAS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
DENV inhibits type I IFN production in infected cells by cleaving human STING
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Activation of STAT6 by STING is critical for antiviral innate immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
STING is a direct innate immune sensor of cyclic di-GMP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095619
retrieved
2 November 2018
Identifiers
DOI
10.1371/JOURNAL.PPAT.1007148
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
PMC publication ID
6095619
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
PubMed publication ID
30114241
1 reference
stated in
Europe PubMed Central
PMC publication ID
6095619
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30114241%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 April 2020
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