(Q57116671)

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Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15662557%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15662557%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

type 2 diabetes

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Eleftheria Zeggini

4

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7 January 2020

Jonathan Cummings Levy

9

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7 January 2020

Stephen O'Rahilly

10

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7 January 2020

13

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7 January 2020

author name string

C F Liew

1

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7 January 2020

C J Groves

2

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7 January 2020

S Wiltshire

3

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7 January 2020

T M Frayling

5

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7 January 2020

K R Owen

6

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7 January 2020

M Walker

7

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7 January 2020

G A Hitman

8

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7 January 2020

A T Hattersley

11

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7 January 2020

D G Johnston

12

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7 January 2020

publication date

15 December 2004

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7 January 2020

1 reference

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7 January 2020

47

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7 January 2020

12

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7 January 2020

2168-2175

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7 January 2020

https://scigraph.springernature.com/pub.10.1007/s00125-004-1575-4

0 references

Base-calling of automated sequencer traces using phred. I. Accuracy assessment

1 reference

https://api.crossref.org/works/10.1007%2FS00125-004-1575-4

21 January 2018

The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes: mellitus or lipidus?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic fat accumulation: an important cause of insulin resistance in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotyping of essential hypertension single-nucleotide polymorphisms by a homogeneous PCR method with universal energy transfer primers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An efficient procedure for genotyping single nucleotide polymorphisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increasing the power and efficiency of disease-marker case-control association studies through use of allele-sharing information

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Etiological investigation of diabetes in young adults presenting with apparent type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growing evidence for diabetes susceptibility genes from genome scan data

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allegro, a new computer program for multipoint linkage analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Base-calling of automated sequencer traces using phred. II. Error probabilities

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GOLD--graphical overview of linkage disequilibrium

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association Studies of Genetic Variation in the WFS1 Gene and Type 2 Diabetes in U.K. Populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of haplotype blocks in the human genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parent-offspring trios: a resource to facilitate the identification of type 2 diabetes genes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipose tissue stearoyl-CoA desaturase mRNA is increased by obesity and decreased by polyunsaturated fatty acids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent insights into stearoyl-CoA desaturase-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing whether an allele can account in part for a linkage signal: the Genotype-IBD Sharing Test (GIST).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triglyceride levels are ethnic-specifically associated with an index of stearoyl-CoA desaturase activity and n-3 PUFA levels in Asians

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of stearoyl-CoA desaturases and role in metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-004-1575-4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15662557%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15662557%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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