(Q57155350)

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An integrated probabilistic framework for cumulative risk assessment of common mechanism chemicals in food: an example with organophosphorus pesticides

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scholarly article

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An integrated probabilistic framework for cumulative risk assessment of common mechanism chemicals in food: an example with organophosphorus pesticides (English)

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Sieto Bosgra

1

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Hilko van der Voet

2

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Polly E Boon

3

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Wout Slob

4

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publication date

July 2009

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Regulatory Toxicology and Pharmacology

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54

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2

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124-33

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Dose addition and the isobole method as approaches for predicting the cumulative effect of non-interacting chemicals: a critical evaluation

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Toxicodynamic analysis of the combined cholinesterase inhibition by paraoxon and methamidophos in human whole blood

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Bootstrap Methods for Standard Errors, Confidence Intervals, and Other Measures of Statistical Accuracy

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Mechanism of action of organophosphorus and carbamate insecticides

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A comparison of three methods for calculating confidence intervals for the benchmark dose.

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Age- and gender-related differences in sensitivity to chlorpyrifos in the rat reflect developmental profiles of esterase activities.

1 reference

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Analysis of the additivity of in vitro inhibition of cholinesterase by mixtures of chlorpyrifos-oxon and azinphos-methyl-oxon

1 reference

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Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach

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Dose-response modeling of continuous endpoints.

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Probabilistic dietary exposure assessment taking into account variability in both amount and frequency of consumption

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A Physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans

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Human risk assessment and TEFs

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Integration of probabilistic exposure assessment and probabilistic hazard characterization.

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A model for probabilistic health impact assessment of exposure to food chemicals.

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10.1016/J.YRTPH.2009.03.004

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