(Q57244922)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785432%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease (English)

1 reference

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8 February 2020

4

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8 February 2020

Pieter Vanden Berghe

7

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8 February 2020

Ludo Van Den Bosch

10

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8 February 2020

author name string

Constantin d'Ydewalle

1

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8 February 2020

Jyothsna Krishnan

2

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8 February 2020

Driss M Chiheb

3

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8 February 2020

Joy Irobi

5

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8 February 2020

Alan P Kozikowski

6

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8 February 2020

Vincent Timmerman

8

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8 February 2020

Wim Robberecht

9

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8 February 2020

language of work or name

English

0 references

publication date

24 July 2011

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8 February 2020

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8 February 2020

volume

17

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8 February 2020

issue

8

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8 February 2020

page(s)

968-974

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https://scigraph.springernature.com/pub.10.1038/nm.2396

8 February 2020

exact match

0 references

cites work

Charcot-Marie-Tooth disease: a clinico-genetic confrontation

1 reference

Mechanisms of disease: a molecular genetic update on hereditary axonal neuropathies

21 January 2018

1 reference

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

21 January 2018

1 reference

The cellular "networking" of mammalian Hsp27 and its functions in the control of protein folding, redox state and apoptosis

21 January 2018

1 reference

Small heat shock proteins in inherited peripheral neuropathies

21 January 2018

1 reference

Heat-shock proteins as death determinants

21 January 2018

1 reference

A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes.

21 January 2018

1 reference

Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1.

21 January 2018

1 reference

Overexpression of growth-associated proteins in the neurons of adult transgenic mice

21 January 2018

1 reference

Axonal neuregulin-1 regulates myelin sheath thickness

21 January 2018

1 reference

CatWalk-assisted gait analysis in the assessment of spinal cord injury

21 January 2018

1 reference

Automated quantitative gait analysis in animal models of movement disorders

21 January 2018

1 reference

The axonal transport of mitochondria.

21 January 2018

1 reference

Post-translational modifications regulate microtubule function

21 January 2018

1 reference

HDAC6 regulates mitochondrial transport in hippocampal neurons

21 January 2018

1 reference

Tubulin modifications and their cellular functions.

21 January 2018

1 reference

HDAC6 is a microtubule-associated deacetylase

21 January 2018

1 reference

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

21 January 2018

1 reference

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

21 January 2018

1 reference

Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A

21 January 2018

1 reference

Relative contribution of mutations in genes for autosomal dominant distal hereditary motor neuropathies: a genotype-phenotype correlation study.

21 January 2018

1 reference

Hindlimb gait defects due to motor axon loss and reduced distal muscles in a transgenic mouse model of Charcot-Marie-Tooth type 2A.

21 January 2018

1 reference

Expression of mitofusin 2(R94Q) in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A.

21 January 2018

1 reference

Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E.

21 January 2018

1 reference

Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption

21 January 2018

1 reference

Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations

21 January 2018

1 reference

Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease

21 January 2018

1 reference

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

21 January 2018

1 reference

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

21 January 2018

1 reference

Mitochondrial and axonal abnormalities precede disruption of the neurofilament network in a model of charcot-marie-tooth disease type 2E and are prevented by heat shock proteins in a mutant-specific fashion.

21 January 2018

1 reference

Role of axonal transport in neurodegenerative diseases

21 January 2018

1 reference

Lysine acetylation targets protein complexes and co-regulates major cellular functions

21 January 2018

1 reference

ER sliding dynamics and ER-mitochondrial contacts occur on acetylated microtubules

21 January 2018

1 reference

Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

21 January 2018

1 reference

Multiple roles of HDAC inhibition in neurodegenerative conditions.

21 January 2018

1 reference

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

21 January 2018

1 reference

HDAC6 is a target for protection and regeneration following injury in the nervous system

21 January 2018

1 reference

HDAC inhibitors and neurodegeneration: at the edge between protection and damage

21 January 2018

1 reference

Characteristics of intermittent mitochondrial transport in guinea pig enteric nerve fibers

21 January 2018

1 reference

Reduction of acetylated alpha-tubulin immunoreactivity in neurofibrillary tangle-bearing neurons in Alzheimer's disease.

21 January 2018

2 references

21 January 2018

12 December 2020

A new locus for autosomal dominant Charcot-Marie-Tooth disease type 2 (CMT2F) maps to chromosome 7q11-q21

1 reference

12 December 2020

A clinical phenotype of distal hereditary motor neuronopathy type II with a novel HSPB1 mutation

1 reference

12 December 2020

Small heat shock protein 27 mutation in a Japanese patient with distal hereditary motor neuropathy

1 reference

12 December 2020

Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice

1 reference

12 December 2020

Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2

1 reference

12 December 2020

Potential role of tubulin acetylation and microtubule-based protein trafficking in familial dysautonomia

1 reference

12 December 2020

Asymmetrical late onset motor neuropathy associated with a novel mutation in the small heat shock protein HSPB1 (HSP27)

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.2396

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785432%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference