(Q57487848)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8788072%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

title

Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: binding and patch clamp studies (English)

1 reference

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19 October 2019

1

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19 October 2019

Christopher G. Parsons

2

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19 October 2019

author name string

S Hartmann

3

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19 October 2019

W Retz

4

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19 October 2019

S Kamolz

5

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19 October 2019

J Thome

6

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19 October 2019

P Riederer

7

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19 October 2019

publication date

1 January 1995

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Journal of Neural Transmission

19 October 2019

published in

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volume

102

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19 October 2019

page(s)

237-246

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19 October 2019

issue

3

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https://scigraph.springernature.com/pub.10.1007/bf01281158

19 October 2019

exact match

0 references

cites work

Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study.

1 reference

12 December 2020

Glutamatergic-dopaminergic balance in the brain. Its importance in motor disorders and schizophrenia

1 reference

12 December 2020

Effects of Antiparkinsonian Drugs on Muscarinic Receptor Binding in Rat Brain, Heart and Lung

1 reference

12 December 2020

Inhibitory effects of the antiparkinsonian drugs memantine and amantadine on N-methyl-D-aspartate-evoked acetylcholine release in the rabbit caudate nucleus in vitro

1 reference

12 December 2020

Comparison of amantadine, orphenadrine, and placebo in the control of phenothiazine-induced Parkinsonism

1 reference

12 December 2020

Behavioural pharmacology of glutamate in the basal ganglia

1 reference

12 December 2020

Suppression by memantine and amantadine of synaptic excitation intrastriatally evoked in rat neostriatal slices

1 reference

12 December 2020

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1 reference

12 December 2020

Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine.

1 reference

12 December 2020

Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties.

1 reference

12 December 2020

Clinical and Pharmacological Review of the Efficacy of Orphenadrine and Its Combination with Paracetamol in Painful Conditions

1 reference

12 December 2020

The anti-parkinsonian drug amantadine inhibits the N-methyl-D-aspartic acid-evoked release of acetylcholine from rat neostriatum in a non-competitive way

1 reference

12 December 2020

Treatment of Parkinson's disease with orphenadrine alone and in combination with L-dopa

1 reference

12 December 2020

A practical computer-based approach to the analysis of radioligand binding experiments

1 reference

12 December 2020

The antiparkinsonian drugs budipine and biperiden are use-dependent (uncompetitive) NMDA receptor antagonists

1 reference

12 December 2020

Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

1 reference

12 December 2020

Combination therapy with haloperidol and orphenadrine in schizophrenia. A clinical and pharmacokinetic study

1 reference

12 December 2020

The antiparkinsonian drug budipine binds to NMDA and sigma receptors in postmortem human brain tissue.

1 reference

12 December 2020

Simple and rapid GLC method for the determination of orphenadrine in human plasma

1 reference

12 December 2020

Toward an understanding of the role of glutamate in experimental parkinsonism: agonist-sensitive sites in the basal ganglia

1 reference

12 December 2020

Regional variations in the pharmacology of NMDA receptor channel blockers: implications for therapeutic potential

1 reference

12 December 2020

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

1 reference

12 December 2020

Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).

1 reference

12 December 2020

Are NMDA antagonistic properties relevant for antiparkinsonian-like activity in rats?--case of amantadine and memantine

1 reference

12 December 2020

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1 reference

12 December 2020

The antiparkinsonian agent budipine is an N-methyl-D-aspartate antagonist.

1 reference

12 December 2020

Orphenadrine plasma levels and amelioration of extrapyramidal side effects in schizophrenic patients treated with haloperidol

1 reference

12 December 2020

Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo

1 reference

12 December 2020

Difference between single and multiple dose pharmacokinetics of orphenadrine hydrochloride in man.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01281158

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8788072%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

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