(Q57711671)

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Dipeptidyl peptidase-4 inhibitor, linagliptin, ameliorates endothelial dysfunction and atherogenesis in normoglycemic apolipoprotein-E deficient mice

scientific article published on 13 August 2015

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22 February 2020

Dipeptidyl peptidase-4 inhibitor, linagliptin, ameliorates endothelial dysfunction and atherogenesis in normoglycemic apolipoprotein-E deficient mice (English)

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22 February 2020

molecular medicine

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Michio Shimabukuro

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22 February 2020

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Hotimah Masdan Salim

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22 February 2020

Daiju Fukuda

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22 February 2020

Yasutomi Higashikuni

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22 February 2020

Kimie Tanaka

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22 February 2020

Yoichiro Hirata

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22 February 2020

Shusuke Yagi

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22 February 2020

Takeshi Soeki

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22 February 2020

Masataka Sata

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22 February 2020

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13 August 2015

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22 February 2020

Vascular Pharmacology

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22 February 2020

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22 February 2020

16-23

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22 February 2020

Atherosclerosis — An Inflammatory Disease

1 reference

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DPP-4 inhibitors and atherosclerosis: the promise

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7 January 2021

Dipeptidyl peptidase-4 inhibitor, sitagliptin, improves endothelial dysfunction in association with its anti-inflammatory effects in patients with coronary artery disease and uncontrolled diabetes

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7 January 2021

Dipeptidyl peptidase-4 inhibitor: another player for cardiovascular protection

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Cardiovascular effects of gliptins

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Cardiovascular actions of incretin-based therapies

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Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways

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7 January 2021

Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease.

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7 January 2021

Exendin-4, a glucagon-like peptide-1 receptor agonist, attenuates neointimal hyperplasia after vascular injury

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7 January 2021

Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E-deficient mice

1 reference

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7 January 2021

Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis

1 reference

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7 January 2021

Preventive effect of dipeptidyl peptidase-4 inhibitor on atherosclerosis is mainly attributable to incretin's actions in nondiabetic and diabetic apolipoprotein E-null mice

1 reference

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7 January 2021

The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms

1 reference

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7 January 2021

Linagliptin: from bench to bedside

1 reference

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7 January 2021

Critical role of bone marrow angiotensin II type 1 receptor in the pathogenesis of atherosclerosis in apolipoprotein E deficient mice.

1 reference

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7 January 2021

Azilsartan, an angiotensin II type 1 receptor blocker, restores endothelial function by reducing vascular inflammation and by increasing the phosphorylation ratio Ser(1177)/Thr(497) of endothelial nitric oxide synthase in diabetic mice

1 reference

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7 January 2021

Clinical implications of cardiovascular preventing pleiotropic effects of dipeptidyl peptidase-4 inhibitors

1 reference

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7 January 2021

Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4.

1 reference

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7 January 2021

DPP-4 inhibitors repress foam cell formation by inhibiting scavenger receptors through protein kinase C pathway

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7 January 2021

Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.

1 reference

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7 January 2021

Endothelial dysfunction: the first step toward coronary arteriosclerosis

1 reference

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7 January 2021

Endothelial dysfunction: a marker of atherosclerotic risk

1 reference

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7 January 2021

Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A.

1 reference

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7 January 2021

Do incretins improve endothelial function?

1 reference

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7 January 2021

Acute DPP-4 inhibition modulates vascular tone through GLP-1 independent pathways

1 reference

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7 January 2021

DPP-4 inhibitor and alpha-glucosidase inhibitor equally improve endothelial function in patients with type 2 diabetes: EDGE study

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2015.08.011

7 January 2021

Cardiovascular effects of glucagon-like peptide 1 (GLP-1) receptor agonists

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2015.08.011

7 January 2021

The DPP-4 inhibitor linagliptin and the GLP-1 receptor agonist exendin-4 improve endothelium-dependent relaxation of rat mesenteric arteries in the presence of high glucose

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2015.08.011

7 January 2021

Glucagon-like peptide-1 activates endothelial nitric oxide synthase in human umbilical vein endothelial cells

1 reference

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7 January 2021

A GLP-1 receptor agonist liraglutide inhibits endothelial cell dysfunction and vascular adhesion molecule expression in an ApoE-/- mouse model.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2015.08.011

7 January 2021

The dipeptidyl peptidase-4 inhibitor teneligliptin improved endothelial dysfunction and insulin resistance in the SHR/NDmcr-cp rat model of metabolic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2015.08.011

7 January 2021

Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition

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7 January 2021

DPP-4 inhibitor linagliptin ameliorates cardiovascular injury in salt-sensitive hypertensive rats independently of blood glucose and blood pressure

1 reference

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7 January 2021

One-year effects of increasingly fat-restricted, carbohydrate-enriched diets on lipoprotein levels in free-living subjects

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Hyperlipidemia-associated renal damage decreases Klotho expression in kidneys from ApoE knockout mice

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Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta

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Eicosapentaenoic acid protects against palmitic acid-induced endothelial dysfunction via activation of the AMPK/eNOS pathway

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7 January 2021

Upregulation of nitric oxide production in vascular endothelial cells by all-trans retinoic acid through the phosphoinositide 3-kinase/Akt pathway.

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7 January 2021

Glucagon-like peptide 1 recruits microvasculature and increases glucose use in muscle via a nitric oxide-dependent mechanism

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7 January 2021

Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA- and PI3K/Akt-dependent pathways and requires GLP-1 receptor

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Coronary artery superoxide production and nox isoform expression in human coronary artery disease

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Obesity and Hypercholesterolemia are Associated with NOX2 Generated Oxidative Stress and Arterial Dysfunction

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Nox2-derived reactive oxygen species contribute to hypercholesterolemia-induced inhibition of neovascularization: effects on endothelial progenitor cells and mature endothelial cells

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Pleiotropic effects of the dipeptidylpeptidase-4 inhibitors on the cardiovascular system

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Dipeptidyl Peptidase 4: A New Link between Diabetes Mellitus and Atherosclerosis?

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Teneligliptin : expectations for its pleiotropic action

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7 January 2021

Identifiers

10.1016/J.VPH.2015.08.011

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26277250%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26277250%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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