(Q57737535)

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Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection

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13 February 2020

Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection (English)

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Europe PubMed Central

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13 February 2020

endoplasmic reticulum

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based on heuristic

inferred from title

genetic diversity

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based on heuristic

inferred from title

Rachele Cagliani

1

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Europe PubMed Central

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13 February 2020

3

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13 February 2020

Matteo Fumagalli

4

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13 February 2020

5

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13 February 2020

Luca Piacentini

8

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13 February 2020

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13 February 2020

10

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13 February 2020

11

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13 February 2020

author name string

Stefania Riva

2

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13 February 2020

Sergio Lo Caputo

6

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13 February 2020

Francesco Mazzotta

7

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13 February 2020

publication date

15 September 2010

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13 February 2020

Human Molecular Genetics

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13 February 2020

19

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13 February 2020

23

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13 February 2020

4705-4714

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13 February 2020

Recent advances in antigen processing and presentation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Pathogen-Driven Selection and Worldwide HLA Class I Diversity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

The nature of selection on the major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Investigating the genetic association between ERAP1 and ankylosing spondylitis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-1.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Genetic risk factors in typical haemolytic uraemic syndrome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Evolutionary signatures of common human cis-regulatory haplotypes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

On the number of segregating sites in genetical models without recombination

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Mathematical model for studying genetic variation in terms of restriction endonucleases

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Genetical structure of populations

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Drift, admixture, and selection in human evolution: a study with DNA polymorphisms

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Interrogating a high-density SNP map for signatures of natural selection

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Balancing selection and its effects on sequences in nearby genome regions

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Median-joining networks for inferring intraspecific phylogenies

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Estimation of divergence times for major lineages of primate species

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Unrooted genealogical tree probabilities in the infinitely-many-sites model.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Sampling theory for neutral alleles in a varying environment.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Population genomic inference of recombination rates and hotspots

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Bayesian inference of fine-scale recombination rates using population genomic data

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Fundamental concepts in genetics: Effective population size and patterns of molecular evolution and variation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Patterns of Human Genetic Diversity: Implications for Human Evolutionary History and Disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Rational inferences about departures from Hardy-Weinberg equilibrium

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Resistance to HIV-1 infection among highly exposed sex workers in Nairobi: what mediates protection and why does it develop?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Targets of balancing selection in the human genome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Endoplasmic reticulum aminopeptidase associated with antigen processing regulates quality of processed peptides presented by MHC class I molecules

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

A New Statistical Method for Haplotype Reconstruction from Population Data

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Haploview: analysis and visualization of LD and haplotype maps

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Libsequence: a C++ class library for evolutionary genetic analysis.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Calibrating a coalescent simulation of human genome sequence variation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Widespread balancing selection and pathogen-driven selection at blood group antigen genes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Efficiency and power in genetic association studies

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

The ‘immunologic advantage’ of HIV-exposed seronegative individuals

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ401

21 January 2018

Identifiers

10.1093/HMG/DDQ401

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20843824%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20843824%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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