(Q57754184)

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The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9350057%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9350057%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

phosphorylation

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author name string

A C Guappone

1

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Europe PubMed Central

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7 November 2019

D C Flynn

2

1 reference

Europe PubMed Central

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7 November 2019

language of work or name

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1 October 1997

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Europe PubMed Central

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7 November 2019

Molecular and Cellular Biochemistry

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Europe PubMed Central

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7 November 2019

175

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7 November 2019

243-252

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Europe PubMed Central

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7 November 2019

1-2

1 reference

Europe PubMed Central

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7 November 2019

https://scigraph.springernature.com/pub.10.1023/a:1006840104666

0 references

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution structure of the SH3 domain of Src and identification of its ligand-binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent binding of peptide ligands to the SH2 and SH3 domains of Grb2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AFAP-120. A variant form of the Src SH2/SH3-binding partner AFAP-110 is detected in brain and contains a novel internal sequence which binds to a 67-kDa protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein modules and signalling networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The GTPase dynamin binds to and is activated by a subset of SH3 domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a Src SH3 domain binding motif by screening a random phage display library.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian origin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular features of the viral and cellular Src kinases involved in interactions with the GTPase-activating protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of pp60c-src protein kinase activity in human colon carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pp60v-src association with the cytoskeleton induces actin reorganization without affecting polymerization status.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation, substrates and functions of src

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SH3 domains direct cellular localization of signaling molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The v-Src SH3 domain binds phosphatidylinositol 3'-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of pp60c-src protein kinase in adult and fetal human tissue: high activities in some sarcomas and mammary carcinomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: identification of a vinculin and pp125Fak-binding region

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of pp60c-src transforming potential by mutations altering the structure of an amino terminal domain containing residues 90-95.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phage display selection of ligand residues important for Src homology 3 domain binding specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pp60c-src activation in human colon carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the SH3 domain of the src oncogene which decrease association of phosphatidylinositol 3'-kinase activity with pp60v-src and alter cellular morphology

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a ten-amino acid proline-rich SH3 binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of Src SH3 ligands from phage-displayed random peptide libraries.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A target for Src in mitosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function analysis of SH3 domains: SH3 binding specificity altered by single amino acid substitutions

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of novel substrates for protein tyrosine kinases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physical and functional interactions between SH2 and SH3 domains of the Src family protein tyrosine kinase p59fyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of a 120,000 dalton membrane-associated protein by the neural form of pp60c-src, pp60c-src+

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the c-src protooncogene in human skin tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of the SH3 domain of Src interferes with regulation by the phosphorylated carboxyl-terminal tyrosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9350057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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