(Q57847240)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Opposing role of Notch1 and Notch2 in a Kras(G12D)-driven murine non-small cell lung cancer model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

non-small-cell lung carcinoma

7 March 2020

main subject

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

author name string

A Baumgart

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

M Anton

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

M Rudelius

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

K Schwamborn

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

A Feuchtinger

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

K Behnke

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

A Walch

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

R Braren

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

C Peschel

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

J Duyster

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

J T Siveke

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

T Dechow

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

language of work or name

English

0 references

publication date

10 February 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

578-588

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2013.592

7 March 2020

exact match

0 references

cites work

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1 reference

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1 reference

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

1 reference

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ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer

21 January 2018

1 reference

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Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo

21 January 2018

1 reference

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Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation

21 January 2018

1 reference

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Alterations of the Notch pathway in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal

21 January 2018

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Notching up a new therapeutic strategy for non-small cell lung carcinoma (NSCLC).

21 January 2018

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Notch1 functions as a tumor suppressor in mouse skin

21 January 2018

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

21 January 2018

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Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

21 January 2018

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The canonical Notch signaling pathway: unfolding the activation mechanism

21 January 2018

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Selective activation of p53-mediated tumour suppression in high-grade tumours

21 January 2018

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Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma

21 January 2018

1 reference

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Notch1 and notch2 have opposite effects on embryonal brain tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.

21 January 2018

1 reference

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The role of Notch in tumorigenesis: oncogene or tumour suppressor?

21 January 2018

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Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation

21 January 2018

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Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

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Stage-specific sensitivity to p53 restoration during lung cancer progression.

21 January 2018

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Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers

21 January 2018

1 reference

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Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway

21 January 2018

1 reference

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Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer

21 January 2018

1 reference

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Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.

21 January 2018

1 reference

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Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis

21 January 2018

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E-cadherin negatively regulates neoplastic growth in non-small cell lung cancer: role of Rho GTPases

21 January 2018

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The E-cadherin cell-cell adhesion complex and lung cancer invasion, metastasis, and prognosis

21 January 2018

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Oncogenic K-Ras regulates proliferation and cell junctions in lung epithelial cells through induction of cyclooxygenase-2 and activation of metalloproteinase-9

21 January 2018

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Immunohistochemical markers associated with brain metastases in patients with nonsmall cell lung carcinoma

21 January 2018

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E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex

21 January 2018

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21 January 2018

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Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo

21 January 2018

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The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma

21 January 2018

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Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Therapeutic antibody targeting of individual Notch receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Activated Notch1 induces lung adenomas in mice and cooperates with Myc in the generation of lung adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo

21 January 2018

1 reference

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Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

The impact of cyclin D1 mRNA isoforms, morphology and p53 in mantle cell lymphoma: p53 alterations and blastoid morphology are strong predictors of a high proliferation index

21 January 2018

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Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.592

The differential effects of mutant p53 alleles on advanced murine lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

Notch2 expression is decreased in colorectal cancer and related to tumor differentiation status

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.592

31 March 2020

Cancer statistics, 2010

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24509876

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24509876

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Notch signaling induces cell cycle arrest in small cell lung cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24509876

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2013.592

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24509876%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference