(Q57956865)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26364617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

The insulin degrading enzyme activates ubiquitin and promotes the formation of K48 and K63 diubiquitin (English)

1 reference

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23 February 2020

1 reference

1

1 reference

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23 February 2020

Valeria Lanza

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26364617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Gaetano Malgieri

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26364617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Adriana Pietropaolo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26364617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Danilo Milardi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26364617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

R Fattorusso

4

1 reference

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23 February 2020

E Rizzarelli

6

1 reference

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23 February 2020

language of work or name

English

0 references

publication date

14 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26364617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

published in

Chemical Communications

1 reference

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23 February 2020

volume

51

1 reference

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23 February 2020

issue

86

1 reference

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23 February 2020

page(s)

15724-15727

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26364617%20AND%20SRC:MED&resulttype=core&format=json

Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones

23 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues

21 January 2018

1 reference

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Overexpression of insulin degrading enzyme: cellular localization and effects on insulin signaling

21 January 2018

1 reference

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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 January 2018

1 reference

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Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-α, and Amylin by Human Insulin-Degrading Enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Insulin has multiple antiamyloidogenic effects on human neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

How the binding and degrading capabilities of insulin degrading enzyme are affected by ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Ubiquitin is a novel substrate for human insulin-degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Insulin-degrading enzyme (IDE): a novel heat shock-like protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Proteasome Activity Is Affected by Fluctuations in Insulin-Degrading Enzyme Distribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

The ubiquitin system for protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Natural history of the E1-like superfamily: implication for adenylation, sulfur transfer, and ubiquitin conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

A neglected modulator of insulin-degrading enzyme activity and conformation: The pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

A spectrophotometric assay for conjugation of ubiquitin and ubiquitin-like proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Inorganic stressors of ubiquitin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Zinc(II) complexes of ubiquitin: speciation, affinity and binding features

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Preparation of distinct ubiquitin chain reagents of high purity and yield.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Insights into the Molecular Composition of Endogenous Unanchored Polyubiquitin Chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Lingering mysteries of ubiquitin-chain assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Inhibition of the 26 S proteasome by polyubiquitin chains synthesized to have defined lengths

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

Ubiquitin dimers control the hydrolase activity of UCH-L3

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5CC06786C

21 January 2018

Identifiers

DOI

10.1039/C5CC06786C

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26364617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference