(Q57980204)

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Regulatable Expression of p21-activated Kinase-1 Promotes Anchorage-independent Growth and Abnormal Organization of Mitotic Spindles in Human Epithelial Breast Cancer Cells

scientific article published in Journal of Biological Chemistry

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9 November 2019

Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells (English)

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9 November 2019

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Mahitosh Mandal

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9 November 2019

Jonathan Chernoff

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9 November 2019

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R K Vadlamudi

1

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9 November 2019

L Adam

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9 November 2019

R A Wang

3

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9 November 2019

D Nguyen

5

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9 November 2019

A Sahin

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9 November 2019

M C Hung

8

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9 November 2019

R Kumar

9

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9 November 2019

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1 November 2000

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9 November 2019

Journal of Biological Chemistry

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9 November 2019

275

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9 November 2019

36238-36244

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9 November 2019

46

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9 November 2019

Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

A role for Rho in Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Signaling through scaffold, anchoring, and adaptor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Inhibition of myosin light chain kinase by p21-activated kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Biological assays for cellular transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

The Phosphorylation Site for Ste20p-like Protein Kinases Is Essential for the Function of Myosin-I in Yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002138200

21 January 2018

Identifiers

10.1074/JBC.M002138200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10945974%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10945974%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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