(Q57987231)

English

Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies

scientific article published in Journal of Biological Chemistry

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory anti-alpha5 and anti-beta1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the alpha5 subunit (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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monoclonal antibody

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based on heuristic

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Yoshikazu Takada

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Martin J. Humphries

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

J A Askari

2

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4 November 2019

S i Aota

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

A Irie

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

H J Mardon

7

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4 November 2019

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publication date

1 July 1997

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4 November 2019

number of pages

10

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Journal of Biological Chemistry

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4 November 2019

272

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4 November 2019

28

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4 November 2019

17283-17292

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Integrin adhesion receptors: structure, function and implications for biomedicine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Dualistic nature of adhesive protein function: fibronectin and its biologically active peptide fragments can autoinhibit fibronectin function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand Occupancy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Critical residues for ligand binding in an I domain-like structure of the integrin beta1 subunit.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Fibronectin receptors of mononuclear phagocytes: binding characteristics and biochemical isolation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Requirement for the synergy site for cell adhesion to fibronectin depends on the activation state of integrin alpha 5 beta 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Isolation and characterization of Chinese hamster ovary cell variants deficient in the expression of fibronectin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Molecular mapping of functional antibody binding sites of alpha 4 integrin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

A secondary structure model of the integrin alpha subunit N-terminal domain based on analysis of multiple alignments

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Possible involvement of the interaction of the alpha 5 subunit of alpha 5 beta 1 integrin with the synergistic region of the central cell-binding domain of fibronectin in cells to fibronectin binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Ligand binding to integrin alphaIIbbeta3 is dependent on a MIDAS-like domain in the beta3 subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

A structure prediction for the ligand-binding region of the integrin beta subunit: evidence for the presence of a von Willebrand factor A domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Integrin activation: the link between ligand binding and signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

The role of the ninth and tenth type III domains of human fibronectin in cell adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.28.17283

21 January 2018

Identifiers

10.1074/JBC.272.28.17283

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9211865%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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