(Q58322383)

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Redesigning the Quaternary Structure of R67 Dihydrofolate Reductase

scientific article published in Journal of Biological Chemistry

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910413%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

Redesigning the quaternary structure of R67 dihydrofolate reductase. Creation of an active monomer from a tetrameric protein by quadruplication of the gene (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910413%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

Elizabeth Howell

6

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21 October 2019

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T D Bradrick

1

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21 October 2019

C Shattuck

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910413%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

M B Strader

3

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21 October 2019

C Wicker

4

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21 October 2019

E Eisenstein

5

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21 October 2019

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1 November 1996

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21 October 2019

Journal of Biological Chemistry

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910413%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

271

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21 October 2019

45

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21 October 2019

28031-28037

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21 October 2019

Design, creation, and characterization of a stable, monomeric triosephosphate isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

The crystal structure of an engineered monomeric triosephosphate isomerase, monoTIM: the correct modelling of an eight-residue loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Engineering the quaternary structure of an enzyme: construction and analysis of a monomeric form of malate dehydrogenase from Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Unusual binding stoichiometries and cooperativity are observed during binary and ternary complex formation in the single active pore of R67 dihydrofolate reductase, a D2 symmetric protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Construction of an altered proton donation mechanism in Escherichia coli dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Purification and properties of Escherichia coli dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Titration of histidine 62 in R67 dihydrofolate reductase is linked to a tetramer<-->two-dimer equilibrium.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Resolution of the fluorescence equilibrium unfolding profile of trp aporepressor using single tryptophan mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

The use of fluorescence methods to monitor unfolding transitions in proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Boundary analysis in sedimentation transport experiments: a procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Construction of a synthetic gene for an R-plasmid-encoded dihydrofolate reductase and studies on the role of the N-terminus in the protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Crystal structure of a novel trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Nucleotide sequence of the dihydrofolate-reductase gene borne by the plasmid R67 and conferring methotrexate resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Characterization of a novel form of thymidylate synthase: a heterodimer isolated after specific chemical modification of the immobilized native enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Communication between catalytic subunits in hybrid aspartate transcarbamoylase molecules: effect of ligand binding to active chains on the conformation of unliganded, inactive chains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Genetic fusion of subunits of a dimeric protein substantially enhances its stability and rate of folding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Synthetic "interface" peptides alter dimeric assembly of the HIV 1 and 2 proteases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Stability and activity of human immunodeficiency virus protease: comparison of the natural dimer with a homologous, single-chain tethered dimer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Redesigning the topology of a four-helix-bundle protein: monomeric Rop.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Covalent attachment of Arc repressor subunits by a peptide linker enhances affinity for operator DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Crystalline Dihydropteroylglutamic Acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Buffers of constant ionic strength for studying pH-dependent processes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Properties of hybrid active sites in oligomeric proteins: kinetic and ligand binding studies with chloramphenicol acetyltransferase trimers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Asymmetry of tyrosyl-tRNA synthetase in solution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Production of linear polymers of HIV gp120-binding domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Construction and characterization of a single polypeptide chain containing two enzymatically active dihydrofolate reductase domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.45.28031

21 January 2018

Identifiers

10.1074/JBC.271.45.28031

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910413%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8910413%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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