(Q58340552)

English

Animal Models for Retinoid Receptor Research: Implications for Epidermal Homeostasis, Skin Barrier Function, Wound Healing, and Atopic Dermatitis

article published in 2007

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scholarly article

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Animal Models for Retinoid Receptor Research: Implications for Epidermal Homeostasis, Skin Barrier Function, Wound Healing, and Atopic Dermatitis (English)

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1 reference

based on heuristic

inferred from title

atopic dermatitis

1 reference

based on heuristic

inferred from title

Norbert B Ghyselinck

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author name string

Norbert B. Ghyselinck

1

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Pierre Chambon

2

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publication date

June 2007

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27-54

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Beyond 'knock-out' mice: new perspectives for the programmed modification of the mammalian genome.

1 reference

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21 January 2018

Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

1 reference

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21 January 2018

The nuclear receptor superfamily: a personal retrospect on the first two decades

1 reference

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21 January 2018

Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis

1 reference

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21 January 2018

Maternal rescue of transforming growth factor-beta 1 null mice

1 reference

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21 January 2018

Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated

1 reference

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21 January 2018

Molecular theory of cancer

1 reference

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21 January 2018

Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome

1 reference

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21 January 2018

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

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21 January 2018

Subregion- and cell type-restricted gene knockout in mouse brain

1 reference

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21 January 2018

Cre-mediated somatic site-specific recombination in mice

1 reference

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21 January 2018

Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments

1 reference

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21 January 2018

Inducible gene targeting in mice

1 reference

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21 January 2018

Recent advances in gene mutagenesis by site-directed recombination

1 reference

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21 January 2018

Conditional gene targeting

1 reference

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21 January 2018

Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase

1 reference

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21 January 2018

Ligand-regulated site-specific recombination

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Ligand-activated site-specific recombination in mice

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

1 reference

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21 January 2018

Site- and time-specific gene targeting in the mouse

1 reference

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21 January 2018

Keith R. Porter Lecture, 1996. Of mice and men: genetic disorders of the cytoskeleton

1 reference

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21 January 2018

The secret life of the hair follicle

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

The biology of hair follicles

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Regulation of terminal differentiation of cultured human keratinocytes by vitamin A.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Hair cycle-specific immunolocalization of retinoic acid synthesizing enzymes Aldh1a2 and Aldh1a3 indicate complex regulation

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Retinoic acid metabolism

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Cellular retinol-binding protein I is essential for vitamin A homeostasis.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Increased neonatal mortality in mice lacking cellular retinol-binding protein II.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Cellular retinol-binding protein type III is needed for retinoid incorporation into milk.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Interactions of retinoid binding proteins and enzymes in retinoid metabolism

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Retinoid-binding proteins: mediators of retinoid action

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

The cellular retinoic acid binding protein I is dispensable.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Conditional (loxP-flanked) allele for the gene encoding the retinoic acid-synthesizing enzyme retinaldehyde dehydrogenase 2 (RALDH2).

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Controlling nuclear receptors: the circular logic of cofactor cycles

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Function of retinoic acid receptor gamma in the mouse

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Dominant-negative retinoic acid receptors elicit epidermal defects through a non-canonical pathway

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Barrier function of the skin: "la raison d'être" of the epidermis

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Novel retinoid X receptor (RXR) antagonists having a dicarba-closo-dodecaborane as a hydrophobic moiety

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

A novel role for helix 12 of retinoid X receptor in regulating repression

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Retinoid X receptors are essential for early mouse development and placentogenesis

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

PPAR gamma is required for placental, cardiac, and adipose tissue development

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Structural Basis for the Barrier Abnormality Following Inhibition of HMG CoA Reductase in Murine Epidermis

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Co-regulator recruitment and the mechanism of retinoic acid receptor synergy

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Principles for modulation of the nuclear receptor superfamily

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Developmental expression of murine retinoid X receptor (RXR) genes.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Isolation and characterization of unsaturated fatty acids as natural ligands for the retinoid-X receptor

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Fatty acids are required for epidermal permeability barrier function

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Splitting hairs: dissecting roles of signaling systems in epidermal development

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Mouse models for the study of human hair loss

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Targeted expression of human vitamin d receptor in the skin promotes the initiation of the postnatal hair follicle cycle and rescues the alopecia in vitamin D receptor null mice

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Genetics of vitamin D 1alpha-hydroxylase deficiency in 17 families

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Ligand-independent actions of the vitamin D receptor maintain hair follicle homeostasis

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Vitamin D receptors repress basal transcription and exert dominant negative activity on triiodothyronine-mediated transcriptional activity

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

New insights into atopic dermatitis

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

New concepts in the pathogenesis of atopic dermatitis

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Keratinocytes in atopic dermatitis: inflammatory signals

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Atopic dermatitis and the atopic march

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Human thymic stromal lymphopoietin: a novel epithelial cell-derived cytokine and a potential key player in the induction of allergic inflammation

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Regulation of B lymphocyte differentiation

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Recombinant human interleukin 5 is a selective activator of human eosinophil function

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Characterization of retinoic acid receptor-deficient keratinocytes

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Retinoic acid receptor gamma mediates topical retinoid efficacy and irritation in animal models.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

EGF receptor ligands

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Epidermal growth factor receptor: mechanisms of activation and signalling.

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Immunohistochemical localization of heparin-binding epidermal growth factor-like growth factor in normal skin and skin cancers

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Soluble form of heparin-binding EGF-like growth factor contributes to retinoic acid-induced epidermal hyperplasia

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

Phosphorylation of activation functions AF-1 and AF-2 of RAR alpha and RAR gamma is indispensable for differentiation of F9 cells upon retinoic acid and cAMP treatment

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

A conditional floxed (loxP-flanked) allele for the retinoic acid receptor gamma (RAR?) gene

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

A conditional floxed (loxP-flanked) allele for the retinoic acid receptor alpha (RARalpha) gene

1 reference

https://api.crossref.org/works/10.3109%2F9781420021189.002

21 January 2018

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10.3109/9781420021189.002

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