(Q58412739)

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Prediction of Therapeutic Responses to Tocilizumab in Patients With Rheumatoid Arthritis: Biomarkers Identified by Analysis of Gene Expression in Peripheral Blood Mononuclear Cells Using Genome-Wide DNA Microarray

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Prediction of Therapeutic Responses to Tocilizumab in Patients With Rheumatoid Arthritis: Biomarkers Identified by Analysis of Gene Expression in Peripheral Blood Mononuclear Cells Using Genome-Wide DNA Microarray (English)

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based on heuristic

inferred from title

rheumatoid arthritis

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Yoshie Sanayama

1

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Kei Ikeda

2

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Yukari Saito

3

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Shin-ichiro Kagami

4

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Mieko Yamagata

5

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Shunsuke Furuta

6

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Daisuke Kashiwakuma

7

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Itsuo Iwamoto

8

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Takeshi Umibe

9

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Yasushi Nawata

10

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Ryutaro Matsumura

11

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Takao Sugiyama

12

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Makoto Sueishi

13

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Masaki Hiraguri

14

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Ken Nonaka

15

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Osamu Ohara

16

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Hiroshi Nakajima

17

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publication date

27 May 2014

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Arthritis & Rheumatology

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66

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1421-1431

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6

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Severe functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine years

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Rheumatoid arthritis

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Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?

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New therapies for treatment of rheumatoid arthritis

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The pathogenesis of rheumatoid arthritis

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Tumour necrosis factor alpha -308G->A polymorphism is not associated with response to TNFalpha blockers in Caucasian patients with rheumatoid arthritis: systematic review and meta-analysis

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Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis

1 reference

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Gene profiling in white blood cells predicts infliximab responsiveness in rheumatoid arthritis

1 reference

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Messenger ribonucleic acid expression profile in peripheral blood cells from RA patients following treatment with an anti-TNF-alpha monoclonal antibody, infliximab

1 reference

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Prediction of efficacy of anti-TNF biologic agent, infliximab, for rheumatoid arthritis patients using a comprehensive transcriptome analysis of white blood cells.

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The gene expression profile in the synovium as a predictor of the clinical response to infliximab treatment in rheumatoid arthritis

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The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patients

1 reference

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Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

1 reference

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1 reference

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Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial

1 reference

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The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1 reference

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Measurement of patient outcome in arthritis

1 reference

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American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis.

1 reference

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Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis. Comparison with the preliminary American College of Rheumatology and the World Health Organization/International League Against Rheumati

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2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

1 reference

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Type I interferons (alpha/beta) in immunity and autoimmunity

1 reference

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Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: assignment of a type I interferon signature in a subpopulation of patients.

1 reference

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Association of the response to tumor necrosis factor antagonists with plasma type I interferon activity and interferon-beta/alpha ratios in rheumatoid arthritis patients: a post hoc analysis of a predominantly Hispanic cohort

1 reference

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Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients

1 reference

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Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases

1 reference

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21 January 2018

Pharmacological induction of interferon type I activity following treatment with rituximab determines clinical response in rheumatoid arthritis

1 reference

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Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment

1 reference

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Pretreatment synovial transcriptional profile is associated with early and late clinical response in rheumatoid arthritis patients treated with rituximab

1 reference

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Inhibition of plasma IL-6 in addition to maintenance of an efficacious trough level of infliximab associated with clinical remission in patients with rheumatoid arthritis: analysis of the RISING Study

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Autoimmune disease complicating antiviral therapy for hepatitis C virus infection

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Interferon Beta treatment in neuromyelitis optica: increase in relapses and aquaporin 4 antibody titers

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Rheumatoid arthritis following PEG-interferon-alfa-2a plus ribavirin treatment for chronic hepatitis C: a case report and review of the literature

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Janus-like effects of type I interferon in autoimmune diseases

1 reference

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Immunopathogenic mechanisms of systemic autoimmune disease

1 reference

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T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis

1 reference

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IL-17 and Th17 Cells

1 reference

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AT-Rich-Interactive Domain-Containing Protein 5A Functions as a Negative Regulator of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γt-Induced Th17 Cell Differentiation

1 reference

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Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling

1 reference

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Human metallothionein genes--primary structure of the metallothionein-II gene and a related processed gene

1 reference

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Structural and functional analysis of the human metallothionein-IA gene: Differential induction by metal ions and glucocorticoids

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Metallothionein: the multipurpose protein

1 reference

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Interleukin 6 regulates metallothionein gene expression and zinc metabolism in hepatocyte monolayer cultures

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Identification of a signal transducer and activator of transcription (STAT) binding site in the mouse metallothionein-I promoter involved in interleukin-6-induced gene expression

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Regulatory role of metallothionein in NF-kappaB activation

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Nutrient-gene interaction in ageing and successful ageing. A single nutrient (zinc) and some target genes related to inflammatory/immune response

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Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis

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Molecular discrimination of responders and nonresponders to anti-TNF alpha therapy in rheumatoid arthritis by etanercept

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10.1002/ART.38400

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