(Q58450597)

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Differential IκB Kinase Activation and IκBα Degradation by Interleukin-1β and Tumor Necrosis Factor-α in Human U937 Monocytic Cells

scientific article published in Journal of Biological Chemistry

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10391945%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

Differential IkappaB kinase activation and IkappaBalpha degradation by interleukin-1beta and tumor necrosis factor-alpha in human U937 monocytic cells. Evidence for additional regulatory steps in kappaB-dependent transcription (English)

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9 December 2019

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9 December 2019

5

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9 December 2019

author name string

Y Nasuhara

1

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9 December 2019

M Catley

3

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9 December 2019

P J Barnes

4

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9 December 2019

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1 July 1999

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9 December 2019

Journal of Biological Chemistry

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9 December 2019

274

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9 December 2019

19965-19972

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9 December 2019

28

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9 December 2019

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Activation and localization of transcription factor, nuclear factor-kappaB, in asthma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Superinduction of NF-kappa B by actinomycin D and cycloheximide in epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Constitutive phosphorylation of I kappa B alpha by casein kinase II.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

All three IkappaB isoforms and most Rel family members are stably associated with the IkappaB kinase 1/2 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Regulation of IkappaBbeta degradation. Similarities to and differences from IkappaBalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Inhibition of TNF-alpha-induced NF-kappaB activation and IL-8 release in A549 cells with the proteasome inhibitor MG-132.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Tumor necrosis factor-alpha activation of nuclear transcription factor-kappaB in marrow macrophages is mediated by c-Src tyrosine phosphorylation of Ikappa Balpha.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Protein-tyrosine kinase activation is required for lipopolysaccharide induction of interleukin 1beta and NFkappaB activation, but not NFkappaB nuclear translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

IkappaBalpha degradation and nuclear factor-kappaB DNA binding are insufficient for interleukin-1beta and tumor necrosis factor-alpha-induced kappaB-dependent transcription. Requirement for an additional activation pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Role of IKK1 and IKK2 in lipopolysaccharide signaling in human monocytic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

A sustained reduction in IkappaB-beta may contribute to persistent NF-kappaB activation in human endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Cloning of a differentially expressed I kappa B-related protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19965

21 January 2018

Identifiers

10.1074/JBC.274.28.19965

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10391945%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10391945%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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