(Q58450602)

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Repression of Cyclooxygenase-2 and Prostaglandin E2Release by Dexamethasone Occurs by Transcriptional and Post-transcriptional Mechanisms Involving Loss of Polyadenylated mRNA

scientific article published in Journal of Biological Chemistry

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6 December 2019

Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA (English)

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6 December 2019

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6 December 2019

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J Seybold

2

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6 December 2019

L M Kuitert

3

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6 December 2019

M Bergmann

4

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6 December 2019

P J Barnes

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6 December 2019

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1 November 1998

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6 December 2019

Journal of Biological Chemistry

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6 December 2019

273

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6 December 2019

48

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6 December 2019

32312-32321

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6 December 2019

Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Cyclooxygenase-2: regulation and relevance in inflammation

1 reference

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21 January 2018

Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo

1 reference

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21 January 2018

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

1 reference

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21 January 2018

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic

1 reference

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21 January 2018

Inhaled glucocorticoids for asthma

1 reference

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21 January 2018

Control of transcription by steroid hormones

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.

1 reference

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21 January 2018

Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

1 reference

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21 January 2018

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

1 reference

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21 January 2018

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor

1 reference

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21 January 2018

Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors

1 reference

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21 January 2018

Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Cytokine induction of cytosolic phospholipase A2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

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21 January 2018

Transcriptional down-regulation of m2 muscarinic receptor gene expression in human embryonic lung (HEL 299) cells by protein kinase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Alternate COX-2 Transcripts Are Differentially Regulated: Implications for Post-Transcriptional Control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Human cyclooxygenase-2 cDNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Superinduction of COX-2 mRNA by cycloheximide and interleukin-1beta involves increased transcription and correlates with increased NF-kappaB and JNK activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Structure of the human cyclo-oxygenase-2 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Manipulation of distinct NFkappaB proteins alters interleukin-1beta-induced human rheumatoid synovial fibroblast prostaglandin E2 formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Effect of dexamethasone on interleukin-1beta-(IL-1beta)-induced nuclear factor-kappaB (NF-kappaB) and kappaB-dependent transcription in epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

1 reference

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21 January 2018

Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes

1 reference

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21 January 2018

DNA binding of the glucocorticoid receptor is not essential for survival

1 reference

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21 January 2018

New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable?

1 reference

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21 January 2018

STAT3 acts as a co-activator of glucocorticoid receptor signaling

1 reference

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21 January 2018

John Zachary Young (1907-97)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.48.32312

21 January 2018

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1 reference

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21 January 2018

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10.1074/JBC.273.48.32312

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9822711%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9822711%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

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