(Q58617296)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

title

Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysema (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

main subject

endoplasmic reticulum

1 reference

0 references

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Steven M Rowe

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

author name string

Israr Ahmad

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Adam Lam

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Matthew A Carlisle

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Changzhao Li

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

J Michael Wells

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

S Vamsee Raju

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Mohammad Athar

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Mark T Dransfield

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Sadis Matalon

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

language of work or name

English

0 references

publication date

2 November 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

Relation of Smoking and Age to Findings in Lung Parenchyma: A Microscopic Study

1 May 2020

cites work

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Concomitant upper-lobe bullous emphysema, lower-lobe interstitial fibrosis and pulmonary hypertension in heavy smokers: report of eight cases and review of the literature

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Clinical characteristics of combined pulmonary fibrosis and emphysema

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Annual changes in pulmonary function in combined pulmonary fibrosis and emphysema: over a 5-year follow-up.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Combined cryptogenic fibrosing alveolitis and emphysema: the value of high resolution computed tomography in assessment

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Images in COPD: Combined Pulmonary Emphysema and Fibrosis with Pulmonary Hypertension

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Combined pulmonary fibrosis and emphysema in patients exposed to agrochemical compounds.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Combined pulmonary fibrosis and emphysema in a tyre industry worker

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Different lung responses to cigarette smoke in two strains of mice sensitive to oxidants

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

A critical review of the American Journal of Physiology-Lung Cellular and Molecular Physiology: 2012-2015.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Angiotensin-(1-7)-mediated Mas1 receptor/NF-κB-p65 signaling is involved in a cigarette smoke-induced chronic obstructive pulmonary disease mouse model

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

A ferret model of COPD-related chronic bronchitis

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Transcriptomic Analysis of Lung Tissue from Cigarette Smoke-Induced Emphysema Murine Models and Human Chronic Obstructive Pulmonary Disease Show Shared and Distinct Pathways

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Phosphodiesterase 4 inhibitor GPD-1116 markedly attenuates the development of cigarette smoke-induced emphysema in senescence-accelerated mice P1 strain.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Reactive airways dysfunction and systemic complaints after mass exposure to bromine

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Case with bromine exposure leading to respiratory insufficiency.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Chemical pneumonitis due to exposure to bromine compounds

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Pneumomediastinum: a complication of exposure to bromine.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Bromofatty aldehyde derived from bromine exposure and myeloperoxidase and eosinophil peroxidase modify GSH and protein

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung Injury

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Osmotic fragility of red blood cells, lipid peroxidation and Ca²⁺-ATPase activity of placental homogenates and red blood cell ghosts in salt-loaded pregnant rats.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Red cells, hemoglobin, heme, iron, and atherogenesis

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

The role of iron in Libby amphibole-induced acute lung injury and inflammation

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Resistance to hyperoxia with heme oxygenase-1 disruption: role of iron

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Intravascular hemolysis and the pathophysiology of sickle cell disease

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhage

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Calcium-dependent phospholipase A2 modulates infection-induced diaphragm dysfunction

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Protein nitration is mediated by heme and free metals through Fenton-type chemistry: an alternative to the NO/O2- reaction

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Heme, heme oxygenase, and ferritin: how the vascular endothelium survives (and dies) in an iron-rich environment

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

ON THE HEME-BINDING CAPACITY OF HEMOPEXIN

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

SEPARATION OF HUMAN HEME- AND HEMOGLOBIN-BINDING PLASMA PROTEINS, CERULOPLASMIN AND ALBUMIN BY GEL FILTRATION

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Role of hemopexin in protection of low-density lipoprotein against hemoglobin-induced oxidation

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

The Binding of Hemoglobin to Haptoglobin and Its Relation to Subunit Dissociation of Hemoglobin

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Identification of the receptor scavenging hemopexin-heme complexes.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Salinomycin induces endoplasmic reticulum stress‑mediated autophagy and apoptosis through generation of reactive oxygen species in human glioma U87MG cells

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Acrolein induces endoplasmic reticulum stress and causes airspace enlargement

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Hemopexin in severe inflammation and infection: mouse models and human diseases

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Endoplasmic reticulum stress, a new wrestler, in the pathogenesis of idiopathic pulmonary fibrosis

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Involvement of endoplasmic reticulum stress in myofibroblastic differentiation of lung fibroblasts.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Pathogenesis of emphysema: from the bench to the bedside

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Salubrinal protects against tunicamycin and hypoxia induced cardiomyocyte apoptosis via the PERK-eIF2α signaling pathway

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Mechanisms and Treatment of Halogen Inhalation-Induced Pulmonary and Systemic Injuries in Pregnant Mice.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Formation of chlorinated lipids post-chlorine gas exposure

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Chlorine inhalation-induced myocardial depression and failure

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Chlorine-induced cardiopulmonary injury

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Nitrite therapy improves survival postexposure to chlorine gas

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Nitrite therapy prevents chlorine gas toxicity in rabbits

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Acute Lung Injury and Persistent Small Airway Disease in a Rabbit Model of Chlorine Inhalation

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Persistent effects of chlorine inhalation on respiratory health

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Centrilobular emphysema combined with pulmonary fibrosis results in improved survival

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Coexistent emphysema delays the decrease of vital capacity in idiopathic pulmonary fibrosis.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Idiopathic pulmonary fibrosis and emphysema: decreased survival associated with severe pulmonary arterial hypertension

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Annual Change in Pulmonary Function and Clinical Characteristics of Combined Pulmonary Fibrosis and Emphysema and Idiopathic Pulmonary Fibrosis: Over a 3-Year Follow-up

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Endoplasmic reticulum stress implicated in the development of renal fibrosis

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Chop Deficiency Protects Mice Against Bleomycin-induced Pulmonary Fibrosis by Attenuating M2 Macrophage Production

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Chlorine induces the unfolded protein response in murine lungs and skin

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

The role of endoplasmic reticulum stress in emphysema results from cigarette smoke exposure

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Severity of elastase-induced emphysema is decreased in tumor necrosis factor-alpha and interleukin-1beta receptor-deficient mice

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Leukocyte elastase induces epithelial apoptosis: role of mitochondial permeability changes and Akt.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Elastase induced lung epithelial cell apoptosis and emphysema through placenta growth factor

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Comparative proteome analysis of peripheral neutrophils from sulfur mustard-exposed and COPD patients.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Human neutrophil elastase induces endothelial cell apoptosis by activating the PERK-CHOP branch of the unfolded protein response.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Asbestos-induced disruption of calcium homeostasis induces endoplasmic reticulum stress in macrophages

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Alpha-1 Antitrypsin-Deficient Macrophages Have Increased Matriptase-Mediated Proteolytic Activity.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Mitochondrial DNA damage via augmented oxidative stress regulates endoplasmic reticulum stress and autophagy: crosstalk, links and signaling

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Oxidative injury in neonatal erythrocytes

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Long-term intercalation of residual hemin in erythrocyte membranes distorts the cell

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Hemolysis of rabbit erythrocytes induced by cigarette smoke

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Antioxidant protection by haemopexin of haem-stimulated lipid peroxidation

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

The influence of heme-binding proteins in heme-catalyzed oxidations

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Cellular protection mechanisms against extracellular heme. heme-hemopexin, but not free heme, activates the N-terminal c-jun kinase

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Hemopexin decreases spontaneous chemiluminescence of cold preserved liver after reperfusion

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Cell-free hemoglobin: a novel mediator of acute lung injury

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental study.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Protective effect of hemopexin on systemic inflammation and acute lung injury in an endotoxemia model.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Haptoglobin or Hemopexin Therapy Prevents Acute Adverse Effects of Resuscitation After Prolonged Storage of Red Cells

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Why does the hemolytic activity of silica predict its pro-inflammatory activity?

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Effect of particle size on quartz-induced hemolysis and on lung inflammation and fibrosis

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Cadmium induces anemia through interdependent progress of hemolysis, body iron accumulation, and insufficient erythropoietin production in rats

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Standardisation of spirometry

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Mitigation of chlorine-induced lung injury by low-molecular-weight antioxidants

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

JoVE: The Journal of Visualized Experiments

24 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238745

10.1172/JCI.INSIGHT.120694

24 October 2020

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30385726%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference