(Q58778818)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30110365%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

title

Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase (English)

1 reference

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18 April 2020

0 references

2

1 reference

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18 April 2020

Amanda H Kahn-Kirby

10

1 reference

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18 April 2020

William D Shrader

20

1 reference

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18 April 2020

author name string

Andrew Hinman

1

1 reference

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18 April 2020

Joey C Latham

3

1 reference

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18 April 2020

Joel J Bruegger

4

1 reference

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18 April 2020

Gözde Ulas

5

1 reference

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18 April 2020

Kevin P McCusker

6

1 reference

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18 April 2020

Akiko Amagata

7

1 reference

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18 April 2020

Dana Davis

8

1 reference

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18 April 2020

Kevin G Hoff

9

1 reference

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18 April 2020

Virna Kim

11

1 reference

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18 April 2020

Yuko Kosaka

12

1 reference

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18 April 2020

Edgar Lee

13

1 reference

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18 April 2020

Stephanie A Malone

14

1 reference

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18 April 2020

Janet J Mei

15

1 reference

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18 April 2020

Steve James Richards

16

1 reference

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18 April 2020

Veronica Rivera

17

1 reference

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18 April 2020

Guy Miller

18

1 reference

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18 April 2020

Jeffrey K Trimmer

19

1 reference

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18 April 2020

language of work or name

English

0 references

publication date

15 August 2018

1 reference

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18 April 2020

1 reference

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18 April 2020

volume

13

1 reference

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18 April 2020

issue

8

1 reference

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18 April 2020

page(s)

e0201369

1 reference

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Creative Commons Attribution 4.0 International

18 April 2020

copyright license

start time

15 August 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

The Potency of Diarylamine Radical-Trapping Antioxidants as Inhibitors of Ferroptosis Underscores the Role of Autoxidation in the Mechanism of Cell Death.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Modulation of Glutathione Hemostasis by Inhibition of 12/15-Lipoxygenase Prevents ROS-Mediated Cell Death after Hepatic Ischemia and Reperfusion.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Ferroptosis Inhibition: Mechanisms and Opportunities

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Complexity of vitamin E metabolism

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

T cell lipid peroxidation induces ferroptosis and prevents immunity to infection.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Interactions between α-tocopherol, polyunsaturated fatty acids, and lipoxygenases during embryogenesis

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

EPI-743 reverses the progression of the pediatric mitochondrial disease--genetically defined Leigh Syndrome.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Towards a modern definition of vitamin E-evidence for a quinone hypothesis.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Initial experience in the treatment of inherited mitochondrial disease with EPI-743.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

α-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Vitamin E biotransformation in humans

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Vitamin E, antioxidant and nothing more

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

30 November 2018

Vitamin E metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Vitamin E oxidation in human atherosclerotic lesions

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Comparison of gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry methods to quantify alpha-tocopherol and alpha-tocopherolquinone levels in human plasma

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Effect of vitamin E on aortic lipid oxidation and intimal proliferation after arterial injury in cholesterol-fed rabbits

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Oxygen-radical absorbance capacity assay for antioxidants

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Reduction of alpha-tocopherolquinone to alpha-tocopherolhydroquinone in rat hepatocytes

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6093661

Reduction of the active-site iron by potent inhibitors of lipoxygenases

30 November 2018

1 reference

12 December 2020

Reductive inactivation of soybean lipoxygenase 1 by catechols: a possible mechanism for regulation of lipoxygenase activity

1 reference

12 December 2020

Synthesis of alpha-tocopherolquinone by the rat and its reduction by mitochondria

1 reference

12 December 2020

Elevated lipid peroxidation and vitamin E-quinone levels in heart ventricles of streptozotocin-treated diabetic rats

1 reference

12 December 2020

The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant

1 reference

12 December 2020

Simultaneous determination of RRR- and SRR-alpha-tocopherols and their quinones in rat plasma and tissues by using chiral high-performance liquid chromatography

1 reference

12 December 2020

Studies of the metabolism of alpha-tocopherol stereoisomers in rats using [5-methyl-(14)C]SRR- and RRR-alpha-tocopherol

1 reference

12 December 2020

Conversion of d-alpha-tocopherol-C14 to tocopheryl-p-quinone in vivo

1 reference

12 December 2020

METABOLIC PRODUCTS OF ALPHA-TOCOPHEROL IN THE LIVERS OF RATS GIVEN INTRAPERITONEAL INJECTIONS OF (14C)-ALPHA-TOCOPHEROL

1 reference

12 December 2020

A0001 in Friedreich ataxia: Biochemical characterization and effects in a clinical trial

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0201369

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30110365%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30110365%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

PubMed publication ID

30110365

1 reference